Evidence map›Paper›PMID 30863028›Full record

Trial reportClinical interventions in aging2019

A game-based neurofeedback training system to enhance cognitive performance in healthy elderly subjects and in patients with amnestic mild cognitive impairment.

Suwicha Jirayucharoensak, Pasin Israsena, Setha Pan-Ngum, Solaphat Hemrungrojn, Michael Maes

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Clinical interventions in aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  3. Efficacy of Neuro-Feedback Training for PTSD Symptoms: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022
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  15. Brain-computer interface: an update for the clinicians.Frontiers in human neuroscience · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Suwicha JirayucharoensakNeural Signal Processing Research Team, Artificial Intelligence Research Unit, National Electronics and Computer Technology Center, Pathum Thani 12120, Thailand, pasin.israsena@nectec.or.th.
Pasin IsrasenaNeural Signal Processing Research Team, Artificial Intelligence Research Unit, National Electronics and Computer Technology Center, Pathum Thani 12120, Thailand, pasin.israsena@nectec.or.th.
Setha Pan-NgumDepartment of Computer Engineering, Faculty of Engineering, Chulalongkorn University, Bangkok 10330, Thailand.
Solaphat HemrungrojnDepartment of Psychiatry, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
Michael MaesDepartment of Psychiatry, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study examines the clinical efficacy of a game-based neurofeedback training (NFT) system to enhance cognitive performance in patients with amnestic mild cognitive impairment (aMCI) and healthy elderly subjects. The NFT system includes five games designed to improve attention span and cognitive performance. The system estimates attention levels by investigating the power spectrum of Beta and Alpha bands.

methodsWe recruited 65 women with aMCI and 54 healthy elderly women. All participants were treated with care as usual (CAU); 58 were treated with CAU + NFT (20 sessions of 30 minutes each, 2-3 sessions per week), 36 with CAU + exergame-based training, while 25 patients had only CAU. Cognitive functions were assessed using the Cambridge Neuropsychological Test Automated Battery both before and after treatment.

resultsNFT significantly improved rapid visual processing and spatial working memory (SWM), including strategy, when compared with exergame training and no active treatment. aMCI was characterized by impairments in SWM (including strategy), pattern recognition memory, and delayed matching to samples.

conclusionIn conclusion, treatment with NFT improves sustained attention and SWM. Nevertheless, NFT had no significant effect on pattern recognition memory and short-term visual memory, which are the other hallmarks of aMCI. The NFT system used here may selectively improve sustained attention, strategy, and executive functions, but not other cognitive impairments, which characterize aMCI in women.

Indexed as

CognitionVideo GamesAgedAttentionCognitive DysfunctionElectroencephalographyExecutive FunctionFemaleHealthy VolunteersHumansMemory, Short-TermNeurofeedbackNeuropsychological TestsPattern Recognition, VisualTreatment Outcomeagingamnestic mild cognitive impairmentbraincognitioncomputer interfaceexecutive functionsneurofeedbackserious gaming

Identifiers

PMID30863028
PMCPMC6388796

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.