ReviewMissouri medicine
Sleep Medicine: Insomnia and Sleep.
Review in Missouri medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05664295 (Comparison of Plasma Orexin-A Levels and Awakening Time From Anesthesia in Patients With and Without Insomnia Who Had Laparoscopic Cholecystectomy Under General Anesthesia), which is not on this map. Cited by 87 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparison of Plasma Orexin-A Levels and Awakening Time From Anesthesia in Patients With and Without Insomnia Who Had Laparoscopic Cholecystectomy Under General Anesthesia
Who cites it
87 citing papers in PubMed, 6 syntheses or guidelines pooled it, 142 citations in OpenAlex.
- Risks Associated With Benzodiazepine Long-Term Use in Chronic Insomnia: A Systematic Review and (Network) Meta-Analysis.Journal of sleep research · 2026Pooled it
- Exploring Occupation-Based Interventions for Sleep Within OTPF: A Systematic Review.Occupational therapy international · 2026Pooled it
- Different doses of dual orexin receptor antagonists in primary insomnia: a Bayesian network analysis.Frontiers in pharmacology · 2023Pooled it
- Cannabinoids in the Treatment of Insomnia Disorder: A Systematic Review and Meta-Analysis.CNS drugs · 2020Pooled it
- [Effects of Aromatherapy on Sleep Quality: A Systematic Review and Meta-Analysis].Journal of Korean Academy of Nursing · 2019Pooled it
- A Meta-Regression of psychosocial factors associated with sleep outcomes in mindfulness-based intervention trials.Behavioral sleep medicinePooled it
- Efficacy and safety of Kami Guibi-tang in older adults with insomnia and memory complaints: a randomized, double-blind, placebo-controlled pilot trial.BMC complementary medicine and therapies · 2026Trial
- Intensive Sleep Retraining and Total Sleep Deprivation for Treating Chronic Insomnia: A Randomised Controlled Trial.Journal of sleep research · 2026Trial
- Transcranial photobiomodulation improves sleep quality, reduces daytime sleepiness, and modulates delta power in chronic insomnia: a randomized controlled trial.Lasers in medical science · 2025Trial
- Efficacy and Safety of Electroacupuncture Combined with Agomelatine Tablets Therapy in Treating Insomnia After Stroke.Journal of molecular neuroscience : MN · 2025Trial
- Effect of a multimodal exercise training program on sleep in older adults: a randomized controlled trial.Brazilian journal of physical therapyTrial
- Acute effects of morning versus evening aerobic exercise on nocturnal blood pressure in healthy young men.Journal of physical therapy science · 2026Article
- Associations between prenatal alcohol exposure and parent-reported sleep disturbances in 10,336 adolescents: an Adolescent Brain Cognitive Development study.Journal of child psychology and psychiatry, and allied disciplines · 2026Article
- Insomnia and associated pharmacological prescription in the adult population in primary care in Central Catalonia from 2018 to 2024.Family medicine and community health · 2026Observational
- The role of sleep disorders in orchestrating proteomic dysfunction and multi-morbidity.Molecular psychiatry · 2026Review
- Associations between sleep hygiene and secondary objective sleep parameters: moving beyond sleep duration.Journal of behavioral medicine · 2026Article
- Insomnia and Its Therapeutic Approaches Among University Students in Madrid.Current therapeutic research, clinical and experimental · 2026Article
- Article
- Sleeping Medications and Prevention of Functional Disability in Older Adults with Low Care Needs: A Prospective Cohort Study.JMA journal · 2026Article
- State-Dependent CNN-GRU Reinforcement Framework for Robust EEG-Based Sleep Stage Classification.Biomimetics (Basel, Switzerland) · 2026Article
27 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Insomnia disorder is an economic burden and public health concern affecting up to one-third of the population of the United States. It is mostly seen in older age groups, and often considered a normal aging phenomenon. The diagnosis and treatment of insomnia rely mainly on a thorough sleep history to address the precipitating factors as well as maladaptive behaviors resulting in poor sleep. It is important for clinicians to recognize and manage the symptoms of insomnia to prevent the morbidity associated with it. This review aims to highlight the pathophysiology, associated comorbidities, clinical evaluation and effective management strategies for insomnia disorder.
Indexed as
Identifiers
30862990PMC6390785W2973929853What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.