Evidence map›Paper›PMID 30862893›Full record

ArticleScientific reports2019

Unraveling RNA dynamical behavior of TPP riboswitches: a comparison between Escherichia coli and Arabidopsis thaliana.

Deborah Antunes, Natasha Andressa Nogueira Jorge, Mauricio Garcia de Souza Costa, Fabio Passetti, Ernesto Raul Caffarena

Open access · goldAbstract readComparative Study
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. X-Ray Crystallography to Study Conformational Changes in a TPP Riboswitch.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  7. Key players in regulatory RNA realm of bacteria.Biochemistry and biophysics reports · 2022
    Review
  8. Riboswitch RSApplied and environmental microbiology · 2022
    Article
  9. Article
  10. RNA biology · 2022
    Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Deborah AntunesComputational Biophysics and Molecular Modeling Group. Scientific Computing Program (PROCC), Fundação Oswaldo Cruz, Rio de Janeiro, 21040-222, Brazil.ORCID 0000-0002-2927-0800
Natasha Andressa Nogueira JorgeLaboratory of Functional Genomics and Bioinformatics, Oswaldo Cruz Institute, Fundação Oswaldo Cruz, Rio de Janeiro, 21040-360, Brazil.
Mauricio Garcia de Souza CostaComputational Biophysics and Molecular Modeling Group. Scientific Computing Program (PROCC), Fundação Oswaldo Cruz, Rio de Janeiro, 21040-222, Brazil.
Fabio PassettiLaboratory of Functional Genomics and Bioinformatics, Oswaldo Cruz Institute, Fundação Oswaldo Cruz, Rio de Janeiro, 21040-360, Brazil.
Ernesto Raul CaffarenaComputational Biophysics and Molecular Modeling Group. Scientific Computing Program (PROCC), Fundação Oswaldo Cruz, Rio de Janeiro, 21040-222, Brazil. ernesto.caffarena@fiocruz.br.
Fundação Oswaldo Cruz · BRFundação Carlos Chagas · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Riboswitches are RNA sensors that affect post-transcriptional processes through their ability to bind to small molecules. Thiamine pyrophosphate (TPP) riboswitch class is the most widespread riboswitch occurring in all three domains of life. Even though it controls different genes involved in the synthesis or transport of thiamine and its phosphorylated derivatives in bacteria, archaea, fungi, and plants, the TPP aptamer has a conserved structure. In this study, we aimed at understanding differences in the structural dynamics of TPP riboswitches from Escherichia coli and Arabidopsis thaliana, based on their crystallographic structures (TPPsw

Indexed as

Molecular Dynamics SimulationRiboswitchThiamine PyrophosphataseArabidopsisEscherichia coliRNA, BacterialRNA, PlantRiboswitchRNA, BacterialRNA, PlantThiamine Pyrophosphatase

Identifiers

PMID30862893
PMCPMC6414600
OpenAlexW2921962529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.