ArticleScientific reports2019
Cytotoxicity of Ag, Au and Ag-Au bimetallic nanoparticles prepared using golden rod (Solidago canadensis) plant extract.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed.
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- Biosynthesis, Characterization, and Antibacterial Activity of Gold, Silver, and Bimetallic Nanoparticles UsingAntibiotics (Basel, Switzerland) · 2024Article
- The Invasive Alien PlantPlants (Basel, Switzerland) · 2024Review
- Harvesting the Power of Green Synthesis: Gold Nanoparticles Tailored for Prostate Cancer Therapy.International journal of molecular sciences · 2024Article
- An Adverse Outcome Pathway for food nanomaterial-induced intestinal barrier disruption.Frontiers in toxicology · 2024Article
- A new vision of photothermal therapy assisted with gold nanorods for the treatment of mammary cancers in adult female rats.Nanoscale advances · 2023Article
- Bioactive ZnO Nanoparticles: Biosynthesis, Characterization and Potential Antimicrobial Applications.Pharmaceutics · 2023Review
- Anticancer Activity of Au/CNT Nanocomposite Fabricated by Nanosecond Pulsed Laser Ablation Method on Colon and Cervical Cancer.Micromachines · 2023Article
- Enhancement of Power Conversion Efficiency of Non-Fullerene Organic Solar Cells Using Green Synthesized Au-Ag Nanoparticles.Polymers · 2023Article
- Green Synthesis of Bioinspired Nanoparticles Mediated from Plant Extracts ofAntibiotics (Basel, Switzerland) · 2023Review
- Biosynthesis of Silver and Gold Nanoparticles and Their Efficacy Towards Antibacterial, Antibiofilm, Cytotoxicity, and Antioxidant Activities.Applied biochemistry and biotechnology · 2023Article
- Recent advances of Au@Ag core-shell SERS-based biosensors.Exploration (Beijing, China) · 2023Review
- Antibacterial Hydrogel Sheet Dressings Composed of Poly(vinyl alcohol) and Silver Nanoparticles by Electron Beam Irradiation.Gels (Basel, Switzerland) · 2023Article
- Biogenic Synthesis of Copper-Based Nanomaterials Using Plant Extracts and Their Applications: Current and Future Directions.Nanomaterials (Basel, Switzerland) · 2022Review
- Biosynthesis of silver nanoparticles using extracts of Stevia rebaudiana and evaluation of antibacterial activity.World journal of microbiology & biotechnology · 2022Article
- Microenvironmental Behaviour of Nanotheranostic Systems for Controlled Oxidative Stress and Cancer Treatment.Nanomaterials (Basel, Switzerland) · 2022Review
- Recent Advances in Green Synthesis, Characterization, and Applications of Bioactive Metallic Nanoparticles.Pharmaceuticals (Basel, Switzerland) · 2022Review
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Production and use of metallic nanoparticles have increased dramatically over the past few years and design of nanomaterials has been developed to minimize their toxic potencies. Traditional chemical methods of production are potentially harmful to the environment and greener methods for synthesis are being developed in order to address this. Thus far phytosynthesis have been found to yield nanomaterials of lesser toxicities, compared to materials synthesized by use of chemical methods. In this study nanoparticles were synthesized from an extract of leaves of golden rod (Solidago canadensis). Silver (Ag), gold (Au) and Ag-Au bimetallic nanoparticles (BNPs), synthesized by use of this "green" method, were evaluated for cytotoxic potency. Cytotoxicity of nanomaterials to H4IIE-luc (rat hepatoma) cells and HuTu-80 (human intestinal) cells were determined by use of the xCELLigence real time cell analyzer. Greatest concentrations (50 µg/mL) of Ag and Ag-Au bimetallic were toxic to both H4IIE-luc and HuTu-80 cells but Au nanoparticles were not toxic. BNPs exhibited the greatest toxic potency to these two types of cells and since AuNPs caused no toxicity; the Au functional portion of the bimetallic material could be assisting in uptake of particles across the cell membrane thereby increasing the toxicity.
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