ArticleThe American journal of case reports2019
Dry Beriberi Due to Thiamine Deficiency Associated with Peripheral Neuropathy and Wernicke's Encephalopathy Mimicking Guillain-Barré syndrome: A Case Report and Review of the Literature.
Article in The American journal of case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Prevalence of thiamine deficiency in anorexia nervosa: a systematic review and narrative synthesis.European child & adolescent psychiatry · 2025Pooled it
- Subclinical thiamine deficiency in third-trimester pregnancy despite routine antenatal supplementation: a cross-sectional study in an urban setting, Bangkok, Thailand.BMC pregnancy and childbirth · 2026Article
- Xenobiotic Hazards in Aircraft Cabin Air.Journal of xenobiotics · 2026Article
- Dry Beriberi During Pregnancy After Hyperemesis Gravidarum: A Case Report of Axonal Sensorimotor Polyneuropathy.Cureus · 2026Article
- Article
- Clinical and Etiopathological Perspective of Vitamin B1 Hypersensitivity and an Example of a Desensitization Protocol.Life (Basel, Switzerland) · 2025Review
- Scoping review of micronutrient imbalances, clinical manifestations, and interventions.World journal of methodology · 2025Review
- Article
- Dry Beriberi and Acute Motor-Sensory Axonal Neuropathy-Induced Paralysis: A Case Report.Cureus · 2025Article
- Thiamine deficiency-related neuropathy: A reversible entity from an endemic area.European journal of neurology · 2024Observational
- A Case of Autoimmune Polyendocrine Syndrome Type 3B and Peripheral Neuropathy Due to Thiamine Deficiency.Cureus · 2024Article
- Suspected Thiamine Deficiency Secondary to Chronic Gastrointestinal Illness: A Case Report.HCA healthcare journal of medicine · 2024Article
- A Rare Case of Thiamine Deficiency Leading to Dry Beriberi, Peripheral Neuropathy, and Torsades De Pointes.Cureus · 2023Article
- Duodenal Adenocarcinoma in the Setting of Bariatric Surgery: A Perfect Storm for Wernicke's Encephalopathy.Cureus · 2023Article
- Thiamine deficiency in pregnancy and lactation: implications and present perspectives.Frontiers in nutrition · 2023Review
- Wernicke Korsakoff syndrome in a teenage female as a complication of COVID-19.Journal of the American College of Emergency Physicians open · 2022Article
- Review
- Thiamine deficiency unrelated to alcohol consumption in high-income countries: a literature review.Annals of the New York Academy of Sciences · 2021Review
- Probable first report of a motor deafferentation syndrome in the Paraguayan War.Arquivos de neuro-psiquiatria · 2021Article
- Nutritional neuropathy postoesophagogastrectomy.BMJ case reports · 2021Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND Beriberi due to thiamine (vitamin B1) deficiency has two clinical presentations. Patients with dry beriberi present with neuropathy, and patients with wet beriberi present with heart failure, with or without neuropathy. Dry beriberi can mimic the most common form of Guillain-Barre syndrome (GBS), an acute inflammatory demyelinating polyradiculoneuropathy (AIDP). Severe thiamine deficiency results in Wernicke's encephalopathy. This report of a case of dry beriberi and Wernicke's encephalopathy due to thiamine deficiency includes a review of the literature. CASE REPORT A 56-year old woman with a history of gallstone pancreatitis and protein-calorie malnutrition was treated six months previously with total parenteral nutrition (TPN). She initially presented at another hospital with paresthesia of the lower limbs, arms, and neck, and symptoms of encephalopathy. Initial diagnosis of GBS was made, based on magnetic resonance imaging (MRI) and cerebrospinal fluid (CSF) findings. Despite five days of intravenous immunoglobulin (IVIG) treatment, her encephalopathy worsened, requiring transfer to our hospital, where she required intubation and treatment with vasopressors. A repeat MRI of her brain showed changes consistent with Wernicke's encephalopathy. Following treatment with high-dose intravenous thiamine, her mental status improved within 48 hours, and by the third hospital day, she no longer required intubation. CONCLUSIONS Symptoms and signs of dry beriberi due to thiamine deficiency can mimic those of acute or chronic GBS. However, thiamine repletion leads to rapid clinical improvement and can prevent irreversible neurologic sequelae, including Korsakoff syndrome. Clinicians should consider thiamine deficiency in malnourished patients presenting with symptoms and signs of GBS.
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