ArticlemBio2019
Genome-Wide Screening for Enteric Colonization Factors in Carbapenem-Resistant ST258 Klebsiella pneumoniae.
Open access · goldAbstract read
In one paragraph
Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 50 citations in OpenAlex.
- A randomized, double-blind, placebo-controlled, single and multiple ascending dose Phase 1 study to determine the safety, pharmacokinetics and food and faecal microbiome effects of ibezapolstat administered orally to healthy subjects.The Journal of antimicrobial chemotherapy · 2020Trial
- An atlas of colonization factors in the human gut microbiome reveals ecological strategies and inflammatory bowel disease signatures.Nature communications · 2026Article
- A posttranslational modification of fimbriae drives pathogenicity inProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Sugar import suppresses Klebsiella pneumoniae Mucoidy in a cAMP-CRP-dependent manner.Nature communications · 2026Article
- Resident and EngraftingbioRxiv : the preprint server for biology · 2026Article
- Genome-wide analysis exploring mechanisms used bymSystems · 2026Article
- Article
- Klebsiella pneumoniae employs a type VI secretion system to overcome microbiota-mediated colonization resistance.Nature communications · 2025Article
- Rapid design of bacteriophage cocktails to suppress the burden and virulence of gut-resident carbapenem-resistant Klebsiella pneumoniae.Cell host & microbe · 2024Article
- Deciphering the gastrointestinal carriage ofInfection and immunity · 2024Review
- Article
- Transposon mutagenesis screen ineLife · 2024Article
- Study of the Genomic Characterization of Antibiotic-ResistantIndian journal of microbiology · 2024Article
- sRNA expression profile of KPC-2-producing carbapenem-resistant Klebsiella pneumoniae: Functional role of sRNA51.PLoS pathogens · 2024Article
- Associations between Nutrigenomic Effects and Incidences of Microbial Resistance against Novel Antibiotics.Pharmaceuticals (Basel, Switzerland) · 2023Review
- Hypermucoviscous Carbapenem-ResistantInternational journal of molecular sciences · 2023Article
- Occurrence and Molecular Study of Hypermucoviscous/Hypervirulence Trait in Gut CommensalMicroorganisms · 2023Article
- Development of Resistance to Eravacycline by Klebsiella pneumoniae and Collateral Sensitivity-Guided Design of Combination Therapies.Microbiology spectrum · 2022Article
- Klebsiella pneumoniae l-Fucose Metabolism Promotes Gastrointestinal Colonization and Modulates Its Virulence Determinants.Infection and immunity · 2022Article
- Lactobacillus supports Clostridiales to restrict gut colonization by multidrug-resistant Enterobacteriaceae.Nature communications · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 1 country.
Hea-Jin JungImmunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA jungh@mskcc.org pamere@mskcc.org.
Eric R LittmannCenter for Microbes, Inflammation, and Cancer, Molecular Microbiology Core Facility, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Ruth SeokImmunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Ingrid M LeinerImmunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Ying TaurCenter for Microbes, Inflammation, and Cancer, Molecular Microbiology Core Facility, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Jonathan PeledAdult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Marcel van den BrinkAdult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Lilan LingCenter for Microbes, Inflammation, and Cancer, Molecular Microbiology Core Facility, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Liang ChenPublic Health Research Institute, New Jersey Medical School, Rutgers, the State University of New Jersey, Newark, New Jersey, USA.
Barry N KreiswirthPublic Health Research Institute, New Jersey Medical School, Rutgers, the State University of New Jersey, Newark, New Jersey, USA.
Andrew L GoodmanDepartment of Microbial Pathogenesis and Microbial Sciences Institute, Yale University School of Medicine, New Haven, Connecticut, USA.
Eric G PamerImmunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA jungh@mskcc.org pamere@mskcc.org.
Memorial Sloan Kettering Cancer Center · USRutgers, The State University of New Jersey · USYale University · US
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4MT LYMPHOCYTE SUBSET FUNCTION POST-TRANSPLANTATIONP01CA023766 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SCHEINBERG, DAVID A · 1985 to 2023
$59.0MSystems Biology of Microbiome-mediated Resilience to Antibiotic-resistant PathogensU01AI124275 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI PAMER, ERIC G., XAVIER, JOAO · 2016 to 2020
$8.9MTNF Mediated Immune Defense Against Listeria InfectionR01AI042135 · NIAID · YALE UNIVERSITY · PI PAMER, ERIC G. · 1998 to 2019
$7.3MThe molecular basis of the epidemic blaKPC gene KlebsiellaR01AI090155 · NIAID · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI KREISWIRTH, BARRY NEAL · 2011 to 2021
$7.2MDissecting the molecular targets to overcome beta-lactam resistance in M. abscessus complexR01AI141805 · NIAID · HACKENSACK UNIVERSITY MEDICAL CENTER · PI BARRY Neal KREISWIRTH · 2019 to 2026
$5.1MInnate Immune Defense against Clostridium Difficile InfectionR01AI095706 · NIAID · UNIVERSITY OF CHICAGO · PI PAMER, ERIC G. · 2012 to 2020
$3.4MMicrobiota mechanisms and biomarkers in GVHDK08HL143189 · NHLBI · SLOAN-KETTERING INST CAN RESEARCH · PI PELED, JONATHAN · 2019 to 2023
$858kNCI NIH HHS P01 CA023766NCI NIH HHS P30 CA008748NHLBI NIH HHS K08 HL143189NIAID NIH HHS R01 AI042135NIAID NIH HHS R01 AI090155NIAID NIH HHS R01 AI095706NIAID NIH HHS U01 AI124275
Abstract
A diverse, antibiotic-naive microbiota prevents highly antibiotic-resistant microbes, including carbapenem-resistant
Indexed as
beta-Lactam ResistanceGenome, BacterialAnimalsAnti-Bacterial AgentsCarbapenemsDisease Models, AnimalDNA Transposable ElementsGenetic TestingKlebsiella InfectionsKlebsiella pneumoniaeMiceMutagenesis, InsertionalVirulence FactorsAnti-Bacterial AgentsCarbapenemsDNA Transposable ElementsVirulence Factorsgenome-wide screeningintestinal colonizationKlebsiella pneumoniaemultidrug resistanceopportunistic infections
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.