Evidence map›Paper›PMID 30862750›Full record

ArticlemBio2019

AtrR Is an Essential Determinant of Azole Resistance in Aspergillus fumigatus.

Sanjoy Paul, Mark Stamnes, Grace Heredge Thomas, Hong Liu, Daisuke Hagiwara, Katsuya Gomi, Scott G Filler, W Scott Moye-Rowley

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
6.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 86 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Molecular and Phenotypic Characterization of Multidrug-ResistantJournal of fungi (Basel, Switzerland) · 2026
    Article
  5. Genotype-Phenotype Relationships in Azole-ResistantJournal of fungi (Basel, Switzerland) · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Azole-ResistantJournal of fungi (Basel, Switzerland) · 2025
    Review
  15. Article
  16. RttA, a ZnMicrobiology spectrum · 2025
    Article
  17. Article
  18. Identification ofFrontiers in veterinary science · 2025
    Article
  19. Review
  20. Review

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Sanjoy PaulDepartment of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Mark StamnesDepartment of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Grace Heredge ThomasDepartment of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Hong LiuDivision of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, USA.
Daisuke HagiwaraFaculty of Life and Environmental Sciences, University of Tsukuba, Ibaraki, Japan.
Katsuya GomiGraduate School of Agricultural Science, Tohoku University, Sendai, Japan.ORCID 0000-0003-3463-8072
Scott G FillerDivision of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, USA.ORCID 0000-0001-7278-3700
W Scott Moye-RowleyDepartment of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA scott-moye-rowley@uiowa.edu.ORCID 0000-0002-7163-1120
University of Iowa · USThe Lundquist Institute · USTohoku University · JPUniversity of California, Los Angeles · USUniversity of Tsukuba · JP

Funding

GENETIC ANALYSIS OF PLEIOTROPIC DRUG RESISTANCER01GM049825 · NIGMS · UNIVERSITY OF IOWA · PI MOYE-ROWLEY, W SCOTT · 1993 to 2019
$6.0M
Candida Invasion of Endothelium and VirulenceR01AI054928 · NIAID · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI FILLER, SCOTT G · 2004 to 2013
$2.9M
Endothelial invasion by yeast-phase CandidaR01AI124566 · NIAID · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI FILLER, SCOTT G, MITCHELL, AARON P · 2016 to 2020
$2.7M
A new pathway for azole resistance in Aspergillus fumigatusR21AI113748 · NIAID · UNIVERSITY OF IOWA · PI MOYE-ROWLEY, W SCOTT · 2015 to 2016
$404k
NIAID NIH HHS R01 AI054928NIAID NIH HHS R01 AI124566NIAID NIH HHS R21 AI113748NIGMS NIH HHS R01 GM049825
6 · The paper itself

Abstract

Aspergillosis associated with azole-resistant

Indexed as

Drug Resistance, FungalRegulonAntifungal AgentsAspergillus fumigatusAzolesChromatin ImmunoprecipitationDNA, FungalElectrophoretic Mobility Shift AssayFungal ProteinsGene DeletionGene Expression ProfilingGene Expression Regulation, FungalMutationPromoter Regions, GeneticProtein BindingSequence Analysis, DNAAntifungal AgentsAzolesDNA, FungalFungal ProteinsTranscription FactorsABC transportersantifungal resistanceAspergillus fumigatusmolecular geneticstranscriptional regulation

Identifiers

PMID30862750
PMCPMC6414702
OpenAlexW2921606435

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.