Evidence map›Paper›PMID 30862621›Full record

ArticleGenetics2019

Split-QF System for Fine-Tuned Transgene Expression in

Olena Riabinina, Samuel W Vernon, Barry J Dickson, Richard A Baines

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Identification ofFrontiers in immunology · 2026
    Review
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  5. The sparse driver system forbioRxiv : the preprint server for biology · 2024
    Article
  6. Article
  7. Toward building a library of cell type-specific drivers across developmental stages.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  8. Review
  9. Article
  10. Maternally Instigated Diapause inFrontiers in behavioral neuroscience · 2022
    Review
  11. Article
  12. Review
  13. Optogenetics in Drosophila.Advances in experimental medicine and biology · 2021
    Review
  14. TheFrontiers in neural circuits · 2020
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Olena RiabininaDivision of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, M13 9PL, United Kingdom oriabinina@gmail.com.ORCID 0000-0002-0088-4534
Samuel W VernonDivision of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, M13 9PL, United Kingdom.
Barry J DicksonJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia 21407.
Richard A BainesDivision of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, M13 9PL, United Kingdom.ORCID 0000-0001-8571-4376
Manchester Academic Health Science Centre · GBJanelia Research Campus · USUniversity of Manchester · GB

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Biotechnology and Biological Sciences Research Council BB/L027690/1NIH HHS P40 OD018537Wellcome TrustWellcome Trust 087742/Z/08/Z
6 · The paper itself

Abstract

The Q-system is a binary expression system that works well across species. Here, we report the development and demonstrate the applications of a split-QF system that drives strong expression in

Indexed as

Gene ExpressionTransgenesAnimalsAnimals, Genetically ModifiedBacterial ProteinsDrosophilaDrosophila ProteinsFemaleGenetic TechniquesLexA Repressor ProteinMaleQuinic AcidSerine EndopeptidasesTranscription FactorsBacterial ProteinsDrosophila ProteinsGAL4 protein, DrosophilaLexA Repressor ProteinQuinic AcidSerine EndopeptidasesTranscription FactorsQ-systemquinic acidsplit-GAL4split-LexA

Identifiers

PMID30862621
PMCPMC6499530
OpenAlexW2896215597

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.