Evidence map›Paper›PMID 30862102›Full record

ArticleJournal of clinical medicine2019

"Can do" versus "do do": A Novel Concept to Better Understand Physical Functioning in Patients with Chronic Obstructive Pulmonary Disease.

Eleonore H Koolen, Hieronymus W van Hees, Rob C van Lummel, Richard Dekhuijzen, Remco S Djamin, Martijn A Spruit, Alex J van 't Hul

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

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  9. Use it or lose it: a four-year follow-up assessing whether physical activity near one's capacity reduces the risk of functional decline among older adults.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2025
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  12. 'Can do' versus 'Do do' in nursing home residents: identification of contextual factors discriminating groups with aligned or misaligned physical activity and physical capacity.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eleonore H KoolenDepartment of Pulmonary Diseases, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands. noortje.koolen@radboudumc.nl.
Hieronymus W van HeesDepartment of Pulmonary Diseases, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands. jeroen.vanhees@radboudumc.nl.
Rob C van LummelMcRobert B.V., 2596 HN The Hague, The Netherlands. r.vanlummel@mcroberts.nl.
Richard DekhuijzenDepartment of Pulmonary Diseases, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands. richard.dekhuijzen@radboudumc.nl.
Remco S DjaminDepartment of Pulmonary Diseases, Amphia Hospital, 4819 EV Breda, The Netherlands. rdjamin@amphia.nl.
Martijn A SpruitDepartment of Research and Education, CIRO+, Center of Expertise for Chronic Organ Failure, 6085 NM Horn, The Netherlands. martijnspruit@ciro-horn.nl.ORCID 0000-0003-3822-7430
Alex J van 't HulDepartment of Pulmonary Diseases, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands. alex.vanthul@radboudumc.nl.ORCID 0000-0002-5514-2327

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPhysical capacity (PC) and physical activity (PA) represent associated but separate domains of physical function. It remains unknown whether this framework may support a better understanding of the impaired physical function in patients with chronic obstructive pulmonary disease (COPD). The current study had two aims: (1) to determine the distribution of patients with COPD over the PC-PA quadrants, and (2) to explore whether differences exist in clinical characteristics between these quadrants.

methodsIn this retrospective study, PC was measured using the six-minute walk distance (6MWD), and PA was assessed with an accelerometer. Moreover, patients' clinical characteristics were obtained. Patients were divided into the following quadrants: (I) low PC (6MWD <70% predicted), low PA, using a step-defined inactivity index (<5000 steps/day, "can't do, don't do" quadrant); (II) preserved PC, low PA ("can do, don't do" quadrant); (III) low PC, preserved PA ("can't do, do do" quadrant); and (IV) preserved PC, preserved PA ("can do, do do" quadrant).

resultsThe distribution of the 662 COPD patients over the quadrants was as follows: "can't do, don't do": 34%; "can do, don't do": 14%; "can't do, do do": 21%; and "can do, do do": 31%. Statistically significant differences between quadrants were found for all clinical characteristics, except for educational levels.

conclusionsThis study proves the applicability of the PC-PA quadrant concept in COPD. This concept serves as a pragmatic clinical tool, that may be useful in the understanding of the impaired physical functioning in COPD patients and therefore, may improve the selection of appropriate interventions to improve physical function.

Indexed as

chronic obstructive pulmonary diseaseexercisephysical activityphysical function

Identifiers

PMID30862102
PMCPMC6463143

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.