Evidence map›Paper›PMID 30862094›Full record

Observational studyBiomolecules2019

The Relationship between Epicardial Adipose Tissue Thickness and Serum Interleukin-17a Level in Patients with Isolated Metabolic Syndrome.

Esra Demir, Nazmiye Özlem Harmankaya, İrem Kıraç Utku, Gönül Açıksarı, Turgut Uygun, Hanise Özkan, Bülent Demir

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Adipogenesis: A Necessary but Harmful Strategy.International journal of molecular sciences · 2019
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Esra DemirDepartment of İnternal Medicine, Kanuni Sultan Süleyman Education and Research Hospital, 34103 İstanbul, Turkey. esracokicli@hotmail.com.
Nazmiye Özlem HarmankayaDepartment of İnternal Medicine, Bakırköy Dr Sadi Konuk Education and Research Hospital, 34147 İstanbul, Turkey. oharmankaya@yahoo.com.
İrem Kıraç UtkuDepartment of İnternal Medicine, Kanuni Sultan Süleyman Education and Research Hospital, 34103 İstanbul, Turkey. iremkrac@yahoo.com.
Gönül AçıksarıDepartment of Cardiology, Medeniyet University Medical Faculty, 34722 İstanbul, Turkey. drgonulkutlu@hotmail.com.
Turgut UygunDepartment of Cardiology, Konya Education and Research Hospital, 42040 Konya, Turkey. turgutuyguncapa@hotmail.com.
Hanise ÖzkanDepartment of İnternal Medicine, Kanuni Sultan Süleyman Education and Research Hospital, 34103 İstanbul, Turkey. haniseozkan@hotmail.com.
Bülent DemirDepartment of Cardiology, Bakırköy Dr Sadi Konuk Education and Research Hospital, 34147 İstanbul, Turkey. drbdmr06@hotmail.com.ORCID 0000-0003-1767-408X
İstanbul Kanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi · TRBakırköy Dr.Sadi Konuk Eğitim ve Araştırma Hastanesi · TRIstanbul Medeniyet University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, it was aimed to investigate the relationship between the epicardial adipose tissue thickness (EATT) and serum IL-17A level insulin resistance in metabolic syndrome patients. This study enrolled a total of 160 subjects, of whom 80 were consecutive patients who applied to our outpatient clinic and were diagnosed with metabolic syndrome, and the other 80 were consecutive patients who were part of the control group with similar age and demographics in whom the metabolic syndrome was excluded. The metabolic syndrome diagnosis was made according to International Diabetes Federation (IDF)-2005 criteria. EATT was measured with transthoracic echocardiography (TTE) in the subjects. IL-17A serum levels were determined using the ELISA method. Fasting blood glucose, HDL, triglyceride, and fasting insulin levels were significantly higher in the metabolic syndrome group compared to the control group. In addition, the metabolic syndrome group had significantly higher high-sensitivity C-reactive protein (hs-CRP) and Homeostatic Model Assessment Insulin Resistance (HOMA-IR) levels than the control group. Similarly, serum IL-17A levels were significantly elevated in the metabolic syndrome group compared to the control group statistically (

Indexed as

Adipose TissueAdultCase-Control StudiesFemaleHumansInterleukin-17MaleMetabolic SyndromeMiddle AgedPericardiumProspective StudiesIL17A protein, humanInterleukin-17adipose tissueinterleukin 17Ametabolic syndrome

Identifiers

PMID30862094
PMCPMC6468684
OpenAlexW2921233414

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.