Trial reportNutrients2019
Pretreatment Fasting Glucose and Insulin as Determinants of Weight Loss on Diets Varying in Macronutrients and Dietary Fibers-The POUNDS LOST Study.
Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Efficacy of a High-Protein Diet to Lower Glycemic Levels in Type 2 Diabetes Mellitus: A Systematic Review.International journal of molecular sciences · 2024Pooled it
- Adaptive dietary and exercise strategies for weight loss in Adults with Prediabetes Trial (ADAPT): a sequential multiple assignment randomized trial.The American journal of clinical nutrition · 2025Trial
- Predicting Factors for Metabolic Non-Response to a Complex Lifestyle Intervention-A Replication Analysis to a Randomized-Controlled Trial.Nutrients · 2022Trial
- High-Protein, Low-Glycaemic Meal Replacement Decreases Fasting Insulin and Inflammation Markers-A 12-Month Subanalysis of the ACOORH Trial.Nutrients · 2021Trial
- Trial
- Review
- Should carbohydrate-modified diets be the first option for weight loss in people with impaired glucose metabolism? A scoping review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2024Article
- A protein-rich meal provides beneficial glycemic and hormonal responses as compared to meals enriched in carbohydrate, fat or fiber, in individuals with or without type-2 diabetes.Frontiers in nutrition · 2024Article
- Dietary protein, amino acids and type 2 diabetes mellitus: a short review.Frontiers in nutrition · 2024Review
- Liver Fat Scores for Noninvasive Diagnosis and Monitoring of Nonalcoholic Fatty Liver Disease in Epidemiological and Clinical Studies.Journal of clinical and translational hepatology · 2023Review
- Precision gestational diabetes treatment: a systematic review and meta-analyses.Communications medicine · 2023Article
- The impact of macronutrient composition on metabolic regulation: An Islet-Centric view.Acta physiologica (Oxford, England) · 2022Article
- Metabotyping for Precision Nutrition and Weight Management: Hype or Hope?Current nutrition reports · 2022Review
- Stimulated Insulin Secretion Predicts Changes in Body Composition Following Weight Loss in Adults with High BMI.The Journal of nutrition · 2022Article
- Sex differences in endocannabinoids during 3 years of Mediterranean diet intervention: Association with insulin resistance and weight loss in a population with metabolic syndrome.Frontiers in nutrition · 2022Article
- Article
- Sexual dimorphism in cardiometabolic health: the role of adipose tissue, muscle and liver.Nature reviews. Endocrinology · 2021Review
- The role of dietary protein in obesity.Reviews in endocrine & metabolic disorders · 2020Review
- Low-carbohydrate diets and cardiometabolic health: the importance of carbohydrate quality over quantity.Nutrition reviews · 2020Review
- Potential Cardiometabolic Health Benefits of Full-Fat Dairy: The Evidence Base.Advances in nutrition (Bethesda, Md.) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
Abstract
Efforts to identify a preferable diet for weight management based on macronutrient composition have largely failed, but recent evidence suggests that satiety effects of carbohydrates may depend on the individual's insulin-mediated cellular glucose uptake. Therefore, using data from the POUNDS LOST trial, pre-treatment fasting plasma glucose (FPG), fasting insulin (FI), and homeostatic model assessment of insulin resistance (HOMA-IR) were studied as prognostic markers of long-term weight loss in four diets differing in carbohydrate, fat, and protein content, while assessing the role of dietary fiber intake. Subjects with FPG <100 mg/dL lost 2.6 (95% CI 0.9;4.4,
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.