Evidence map›Paper›PMID 30861371›Full record

ArticleDevelopmental cell2019

Breaking Symmetry: Worm Cue Finally Found.

Bruce Bowerman, Kenji Sugioka

Open access · bronzeAbstract readComment
In one paragraph

Article in Developmental cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Bruce BowermanInstitute of Molecular Biology, University of Oregon, Eugene, OR 97403, USA. Electronic address: bowerman@uoregon.edu.
Kenji SugiokaDepartment of Zoology, Life Sciences Institute, University of British Columbia, Vancouver, BC V6T1Z3, Canada.
University of British Columbia · CAUniversity of Oregon · US

Funding

Mitotic Spindle Assembly & Function in C. elegans - Equipment SupplementR01GM049869 · NIGMS · UNIVERSITY OF OREGON · PI BOWERMAN, BRUCE A · 1994 to 2019
$6.5M
Cytoskeletal Function in C. elegans EmbryosR35GM131749 · NIGMS · UNIVERSITY OF OREGON · PI BRUCE A BOWERMAN · 2019 to 2026
$4.8M
NIGMS NIH HHS R01 GM049869NIGMS NIH HHS R35 GM131749
6 · The paper itself

Abstract

In this issue of Developmental Cell, Zhao et al. (2019) show that the Aurora A kinase AIR-1 is the long-sought cue that downregulates cortical actomyosin to establish anterior-posterior polarity in the C. elegans zygote, diffusing from centrosomes to the overlying cortex to phosphorylate yet to be identified target(s).

Indexed as

ActomyosinCaenorhabditis elegans ProteinsAnimalsAurora Kinase ACaenorhabditis elegansCentrosomeCuesActomyosinair-1 protein, C elegansAurora Kinase ACaenorhabditis elegans Proteins

Identifiers

PMID30861371
PMCPMC7685514
OpenAlexW2922524777

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.