Evidence map›Paper›PMID 30861042›Full record

Trial reportPloS one2019

The effect of a pharmacy-led transitional care program on medication-related problems post-discharge: A before-After prospective study.

Sara Daliri, Jacqueline G Hugtenburg, Gerben Ter Riet, Bart J F van den Bemt, Bianca M Buurman, Wilma J M Scholte Op Reimer, Marie-Christine van Buul-Gast, Fatma Karapinar-Çarkit

Open access · goldAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.

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  8. Patient perspectives on nurse-led follow-up calls after head and neck surgery.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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  9. Bridging the Gap Between Inpatient and Outpatient Care.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2024
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  17. Pharmacist-Led Discharge Transitions of Care Interventions for Pediatric Patients: A Narrative Review.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Sara DaliriFaculty of Health, Amsterdam University of Applied Sciences, Amsterdam, the Netherlands.ORCID 0000-0003-3999-3444
Jacqueline G HugtenburgDepartment of Clinical Pharmacology & Pharmacy, VU University Medical Center, Amsterdam, the Netherlands.
Gerben Ter RietDepartment of General Practice, Academic Medical Center, Amsterdam, the Netherlands.
Bart J F van den BemtDepartment of Pharmacy, Sint Maartenskliniek, Nijmegen, the Netherlands.
Bianca M BuurmanFaculty of Health, Amsterdam University of Applied Sciences, Amsterdam, the Netherlands.
Wilma J M Scholte Op ReimerFaculty of Health, Amsterdam University of Applied Sciences, Amsterdam, the Netherlands.
Marie-Christine van Buul-GastDepartment of Hospital Pharmacy, BovenIJ Hospital, Amsterdam, the Netherlands.
Fatma Karapinar-ÇarkitDepartment of Clinical Pharmacy, OLVG Hospital, Amsterdam, the Netherlands.
Amsterdam UMC Location University of Amsterdam · NLAmsterdam UMC Location Vrije Universiteit Amsterdam · NLOLVG · NLRadboud University Nijmegen · NLRijnstate Hospital · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMedication-related problems are common after hospitalization, for example when changes in patients' medication regimens are accompanied by insufficient patient education, poor information transfer between healthcare providers, and inadequate follow-up post-discharge. We investigated the effect of a pharmacy-led transitional care program on the occurrence of medication-related problems four weeks post-discharge.

methodsA prospective multi-center before-after study was conducted in six departments in total of two hospitals and 50 community pharmacies in the Netherlands. We tested a pharmacy-led program incorporating (i) usual care (medication reconciliation at hospital admission and discharge) combined with, (ii) teach-back at hospital discharge, (iii) improved transfer of medication information to primary healthcare providers and (iv) post-discharge home visit by the patient's own community pharmacist, compared with usual care alone. The difference in medication-related problems four weeks post-discharge, measured by means of a validated telephone-interview protocol, was the primary outcome. Multiple logistic regression analysis was used, adjusting for potential confounders after multiple imputation to deal with missing data.

resultsWe included 234 (January-April 2016) and 222 (July-November 2016) patients in the usual care and intervention group, respectively. Complete data on the primary outcome was available for 400 patients. The proportion of patients with any medication-related problem was 65.9% (211/400) in the usual care group compared to 52.4% (189/400) in the intervention group (p = 0.01). After multiple imputation, the proportion of patients with any medication-related problem remained lower in the intervention group (unadjusted odds ratio 0.57; 95% CI 0.38-0.86, adjusted odds ratio 0.50; 95% CI 0.31-0.79).

conclusionsA pharmacy-led transitional care program reduced medication-related problems after discharge. Implementation research is needed to determine how best to embed these interventions in existing processes.

Indexed as

Patient DischargeTransitional CareAgedAged, 80 and overFemaleHumansMaleMiddle AgedNetherlandsPharmacistsPharmacyProspective Studies

Identifiers

PMID30861042
PMCPMC6413946
OpenAlexW2921362599

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.