Evidence map›Paper›PMID 30860995›Full record

SynthesisPLoS neglected tropical diseases2019

Strongyloides stercoralis infection: A systematic review of endemic cases in Spain.

Maria Barroso, Fernando Salvador, Adrián Sánchez-Montalvá, Pau Bosch-Nicolau, Israel Molina

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in PLoS neglected tropical diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Article
  4. Article
  5. Article
  6. Article
  7. Molecular taxonomic study ofFrontiers in parasitology · 2026
    Article
  8. Article
  9. The Seroepidemiology ofJournal of tropical medicine · 2024
    Article
  10. Review
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  12. Seroprevalence ofTropical medicine and infectious disease · 2023
    Article
  13. Article
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  15. Article
  16. Article
  17. Eosinophilic appendicitis due toBMJ case reports · 2021
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Maria BarrosoPrimary Health Centre La Marina, Autonomous University of Barcelona, Barcelona, Spain.ORCID 0000-0003-1262-8359
Fernando SalvadorDepartment of Infectious Diseases, Vall d'Hebron University Hospital, PROSICS Barcelona, Spain.ORCID 0000-0002-0546-1354
Adrián Sánchez-MontalváDepartment of Infectious Diseases, Vall d'Hebron University Hospital, PROSICS Barcelona, Spain.
Pau Bosch-NicolauDepartment of Infectious Diseases, Vall d'Hebron University Hospital, PROSICS Barcelona, Spain.
Israel MolinaDepartment of Infectious Diseases, Vall d'Hebron University Hospital, PROSICS Barcelona, Spain.
Vall d'Hebron Hospital Universitari · ESUniversitat Autònoma de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStrongyloides stercoralis infection, a neglected tropical disease, is widely distributed. Autochthonous cases have been described in Spain, probably infected long time ago. In recent years the number of diagnosed cases has increased due to the growing number of immigrants, travelers and refugees, but endemically acquired cases in Spain remains undetermined. METHODOLOGY: We systematically searched the literature for references on endemic strongyloidiasis cases in Spain. The articles were required to describe Strongyloides stercoralis infection in at least one Spanish-born person without a history of travel to endemic areas and be published before 31st May 2018. Epidemiological data from patients was collected and described individually as well as risk factors to acquisition of the infection, diagnostic technique that lead to the diagnosis, presence of eosinophilia and clinical symptoms at diagnosis.

findingsThirty-six studies were included, describing a total of 1083 patients with an average age of 68.3 years diagnosed with endemic strongyloidiasis in Spain. The vast majority of the cases were described in the province of Valencia (n = 1049). Two hundred and eight of the 251 (82.9%) patients in whom gender was reported were male, and most of them had current or past dedication to agriculture. Seventy percent had some kind of comorbidity. A decreasing trend in the diagnosed cases per year is observed from the end of last decade. However, there are still nefigw diagnoses of autochthonous cases of strongyloidiasis in Spain every year.

conclusionsWith the data provided by this review it is likely that in Spain strongyloidiasis might have been underestimated. It is highly probable that the infection remains undiagnosed in many cases due to low clinical suspicion among Spanish population without recent travel history in which the contagion probably took place decades ago.

Indexed as

Endemic DiseasesAgedAnimalsEosinophiliaFecesFemaleHumansMaleRisk FactorsSpainSputumStrongyloides stercoralisStrongyloidiasis

Identifiers

PMID30860995
PMCPMC6413904
OpenAlexW2922395247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.