ArticleOrganic letters2019
Photoredox Radical/Polar Crossover Enables Construction of Saturated Nitrogen Heterocycles.
Article in Organic letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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Who cites it
19 citing papers in PubMed.
- Photocatalytic Annulation of Primary Amines to δ-Lactams: Access to Privileged (Spiro)piperidine Space.Organic letters · 2026Article
- Radical Sampling Enabled Saturated N-Heterocycle Cyclization.Journal of the American Chemical Society · 2026Article
- Photocatalyzed Ring Expansion of α-Ketosulfonylaziridines: Ready Access to δ-Sultams.Angewandte Chemie (International ed. in English) · 2026Article
- Alkene Carboxy-Alkylation via COJournal of the American Chemical Society · 2024Article
- Glycine-Based [3+2] Cycloaddition for the Synthesis of Pyrrolidine-Containing Polycyclic Compounds.Molecules (Basel, Switzerland) · 2024Review
- 3-Chloropropylbis(catecholato)silicate as a Bifunctional Reagent for the One-Pot Synthesis of Tetrahydroquinolines fromThe Journal of organic chemistry · 2024Article
- High-throughput synthesis provides data for predicting molecular properties and reaction success.Science advances · 2023Article
- Recent Advances in the Green Synthesis of ActivePharmaceuticals (Basel, Switzerland) · 2023Review
- Excited-state palladium-catalysed reductive alkylation of imines: scope and mechanism.Chemical science · 2022Article
- Mechanism of Visible Light-Mediated Alkene Aminoarylation with Arylsulfonylacetamides.ACS catalysis · 2022Article
- Accessing IllusiveOrganic letters · 2022Article
- Synthesis of piperidine and pyrrolidine derivatives by electroreductive cyclization of imine with terminal dihaloalkanes in a flow microreactor.Beilstein journal of organic chemistry · 2022Article
- Pd-catalyzed [3 + 2] cycloaddition of cyclic ketimines and trimethylenemethanes towardRSC advances · 2021Article
- Diastereocontrol in Radical Addition to β-Benzyloxy Hydrazones: Revised Approach to Tubuvaline and Synthesis ofThe Journal of organic chemistry · 2021Article
- Reductive radical-initiated 1,2-C migration assisted by an azidyl group.Chemical science · 2020Article
- Photoredox-Mediated Net-Neutral Radical/Polar Crossover Reactions.Israel journal of chemistry · 2020Article
- Radical-Polar Crossover Annulation: A Platform for Accessing Polycyclic Cyclopropanes.Advanced synthesis & catalysis · 2020Article
- Alkyl Radical Addition to Aliphatic and AromaticOrganic letters · 2019Article
- Reductive radical-polar crossover: traditional electrophiles in modern radical reactions.Chemical science · 2019Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Photoredox-mediated radical/polar crossover (RPC) processes offer new avenues for the synthesis of cyclic molecules. This process has been realized for the construction of medium-sized saturated nitrogen heterocycles. Photocatalytically generated alkyl radicals possessing pendant leaving groups engage imines in C-C bond formation, and subsequent reduction of the intermediate nitrogen-centered radical triggers anionic ring closure. With the aid of visible light irradiation, substituted pyrrolidines, piperidines, and azepanes can be prepared under mild, redox-neutral conditions.
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Registered trials
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