ArticleThe American journal of tropical medicine and hygiene2019
Complex Epidemiological Dynamics of Eastern Equine Encephalitis Virus in Florida.
Article in The American journal of tropical medicine and hygiene, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The trial behind it
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Who cites it
12 citing papers in PubMed, 26 citations in OpenAlex.
- Eastern equine encephalitis virus and identification of host bloodmeal sources from individual Culiseta melanura (Diptera: Culicidae) at an enzootic focus in central New York State.Journal of medical entomology · 2026Article
- Review
- Rapid detection of West Nile and Dengue viruses from mosquito saliva by loop-mediated isothermal amplification and displaced probes.PloS one · 2024Article
- Eastern Equine Encephalitis Virus Diversity in Massachusetts Patients, 1938-2020.The American journal of tropical medicine and hygiene · 2023Article
- Efficacy of a brain-penetrant antiviral in lethal Venezuelan and eastern equine encephalitis mouse models.Science translational medicine · 2023Article
- Spatiotemporal Environmental Drivers of Eastern Equine Encephalitis Virus in Central Florida: Towards a Predictive Model for a Lethal Disease.Journal of medical entomology · 2022Article
- Article
- Four Human Cases of Eastern Equine Encephalitis in Connecticut, USA, during a Larger Regional Outbreak, 2019.Emerging infectious diseases · 2021Review
- Mosquito Control Priorities in Florida-Survey Results from Florida Mosquito Control Districts.Pathogens (Basel, Switzerland) · 2021Article
- Fatal Human Infection with Evidence of Intrahost Variation of Eastern Equine Encephalitis Virus, Alabama, USA, 2019.Emerging infectious diseases · 2021Article
- Eastern Equine Encephalitis Virus: A Scoping Review of the Global Evidence.Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2021Article
- Epidemic Alphaviruses: Ecology, Emergence and Outbreaks.Microorganisms · 2020Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Eastern equine encephalitis virus (EEEV) infection results in high mortality in infected horses and humans. Florida has been identified as an important source of EEEV epidemics to other states in the United States. In this study, we further characterized the epidemiological and evolutionary dynamics of EEEV in Florida. Epidemiological analysis of sentinel chicken seroconversion rates to EEEV infections during 2005-2016 suggested significant seasonality of EEEV activity in Florida. We observed significant annual activity of EEEV in the North and North Central regions, with little significant seasonality in the Panhandle region. Phylogenetic analysis of complete EEEV genome sequences from different host sources and regions in Florida during 1986-2014 revealed extensive genetic diversity and spatial dispersal of the virus within Florida and relatively more clustering of the viruses in the Panhandle region. We found no significant association between EEEV genetic variation and host source. Overall, our study revealed a complex epidemiological dynamic of EEEV within Florida, implicating the Panhandle region as a possible source of the virus with sustained year-round transmission. These findings will help in implementing targeted control measures that can have the most impact in reducing or eliminating EEEV and other mosquito-borne viral infections within Florida and in the rest of the United States.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.