Evidence map›Paper›PMID 30860013›Full record

ArticleThe American journal of tropical medicine and hygiene2019

Prevalence of and Risk Factors Associated with Polymerase Chain Reaction-Determined

Richard Mwaiswelo, Billy Ngasala, Irina Jovel, Weiping Xu, Erik Larsson, Maja Malmberg, Jose Pedro Gil, Zul Premji, Bruno P Mmbando, Andreas Mårtensson

Registry-linked trialAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05764746 (Can Triple Artemisinin-based Combination Therapy for Treatment of Uncomplicated Plasmodium Falciparum Malaria, Delay Drug Resistance Development of Plasmodium Falciparum in Tanzania), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05764746 phase2 / phase3completednot on this mapstarted 2023, after this paper: background citation

Can Triple Artemisinin-based Combination Therapy for Treatment of Uncomplicated Plasmodium Falciparum Malaria, Delay Drug Resistance Development of Plasmodium Falciparum in Tanzania: a Randomized Three Arm Clinical Trial

TypeinterventionalSponsorMuhimbili University of Health and Allied SciencesRan2023 to 2025Enrolled384ConditionsUncomplicated Plasmodium Falciparum MalariaArmsArtemether-lumefantrine and Amodiaquine Drug Combination, Artemether-lumefantrine then Artesunate amodiaquine, Artemether-lumefantrine
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Day 3 parasitemia andmedRxiv : the preprint server for health sciences · 2024
    Article
  6. Article
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  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Detection ofThe American journal of tropical medicine and hygiene · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Richard MwaisweloDepartment of Parasitology and Medical Entomology, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Billy NgasalaDepartment of Women's and Children's Health, International Maternal and Child Health (IMCH), Uppsala Universitet, Uppsala, Sweden.
Irina JovelDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Weiping XuDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Erik LarssonDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Maja MalmbergSLU Global Bioinformatics Centre, Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Jose Pedro GilDrug Resistance Unit, Division of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
Zul PremjiAga Khan University Hospital, Nairobi, Kenya.
Bruno P MmbandoTanga Centre, National Institute for Medical Research, Tanga, Tanzania.
Andreas MårtenssonDepartment of Women's and Children's Health, International Maternal and Child Health (IMCH), Uppsala Universitet, Uppsala, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prevalence of and risk factors associated with polymerase chain reaction (PCR)-determined

Indexed as

AdolescentAntimalarialsArtemether, Lumefantrine Drug CombinationChildChild, PreschoolDNA, ProtozoanFemaleHumansInfantMalaria, FalciparumMaleParasitemiaPlasmodium falciparumPolymerase Chain ReactionPrevalencePrimaquineAntimalarialsArtemether, Lumefantrine Drug CombinationDNA, ProtozoanPrimaquine

Identifiers

PMID30860013
PMCPMC6493965

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.