Evidence map›Paper›PMID 30860010›Full record

ArticleThe American journal of tropical medicine and hygiene2019

Global Outbreaks and Origins of a Chikungunya Virus Variant Carrying Mutations Which May Increase Fitness for

Irina Maljkovic Berry, Fredrick Eyase, Simon Pollett, Samson Limbaso Konongoi, Michael Gordon Joyce, Katherine Figueroa, Victor Ofula, Helen Koka, Edith Koskei, Albert Nyunja and 3 more

Open access · hybridAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
9.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Chikungunya fever in Africa: a systematic review.Pathogens and global health · 2020
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Chikungunya outbreak in eastern Senegal, 2023.BMC infectious diseases · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Irina Maljkovic BerryViral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland.
Fredrick EyaseUnited States Army Medical Research Directorate - Kenya, Nairobi, Kenya.
Simon PollettViral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland.
Samson Limbaso KonongoiCenter for Virus Research, Kenya Medical Research Institute, Nairobi, Kenya.
Michael Gordon JoyceHenry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, Maryland.
Katherine FigueroaViral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland.
Victor OfulaUnited States Army Medical Research Directorate - Kenya, Nairobi, Kenya.
Helen KokaUnited States Army Medical Research Directorate - Kenya, Nairobi, Kenya.
Edith KoskeiUnited States Army Medical Research Directorate - Kenya, Nairobi, Kenya.
Albert NyunjaUnited States Army Medical Research Directorate - Kenya, Nairobi, Kenya.
James D MancusoUnited States Army Medical Research Directorate - Kenya, Nairobi, Kenya.
Richard G JarmanViral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland.
Rosemary SangUnited States Army Medical Research Directorate - Kenya, Nairobi, Kenya.
United States Army Medical Research Directorate - Africa · KEWalter Reed Army Institute of Research · USHenry M. Jackson Foundation · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 2016, a chikungunya virus (CHIKV) outbreak was reported in Mandera, Kenya. This was the first major CHIKV outbreak in the country since the global reemergence of this virus in Kenya in 2004. We collected samples and sequenced viral genomes from this outbreak. All Kenyan genomes contained two mutations, E1:K211E and E2:V264A, recently reported to have an association with increased infectivity, dissemination, and transmission in the

Indexed as

Disease OutbreaksGenetic FitnessGenetic VariationMutationAedesAnimalsBangladeshChikungunya FeverChikungunya virusGenome, ViralHumansIndiaKenyaMosquito VectorsPhylogenyRNA, ViralRNA, Viral

Identifiers

PMID30860010
PMCPMC6493958
OpenAlexW2921204183

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.