Evidence map›Paper›PMID 30859796›Full record

ArticleJournal of clinical research in pediatric endocrinology2019

Intrauterine Twin Discordancy and Partial Postnatal Catch-up Growth in a Girl with a Pathogenic

Paula Ocaranza, Monique Losekoot, Marie J. E. Walenkamp, Christiaan De Bruin, Jan M. Wit, Veronica Mericq

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PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical research in pediatric endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Paula OcaranzaUniversity of Chile Faculty of Medicine, Institute of Maternal and Child Research, Santiago, ChileORCID 0000-002-1681-6122
Monique LosekootLeiden University Medical Center, Department of Clinical Genetics, Leiden, The NetherlandsORCID 0000-0002-7272-5137
Marie J. E. WalenkampEmma Children’s Hospital, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Department of Pediatric Endocrinology, Amsterdam, The NetherlandsORCID 0000-0002-5860-7679
Christiaan De BruinLeiden University Medical Center, Department of Pediatrics, Leiden, The NetherlandsORCID 0000-0003-1478-2261
Jan M. WitLeiden University Medical Center, Department of Pediatrics, Leiden, The NetherlandsORCID 0000-0002-1715-5020
Veronica MericqUniversity of Chile Faculty of Medicine, Institute of Maternal and Child Research, Santiago, ChileORCID 0000-0003-2287-0181
Leiden University Medical Center · NLUniversity of Chile · CLEmma Kinderziekenhuis · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Insulin like growth factors-1 (IGF-1) is essential for normal Methods: A girl born with a low weight and length [-2.3 and -2.4 standard deviation (SD) score (SDS), respectively] but borderline low head circumference (-1.6 SD) presented with a height of -1.7 SDS, in contrast to a normal height twin brother (0.0 SDS). IGF-1 resistance was suspected because of elevated serum IGF-1 levels. Results: Sequencing revealed the presence of a previously described pathogenic heterozygous mutation (p.Glu1050Lys) in the SGA girl which was not present in the parents nor in the AGA twin brother. Conclusion: The pathogenic

Indexed as

MutationBody HeightFailure to ThriveFemaleFetal Growth RetardationGestational AgeHumansInfant, NewbornInfant, Small for Gestational AgeInsulin-Like Growth Factor IMalePrognosisReceptor, IGF Type 1Twins, DizygoticIGF1R protein, humanInsulin-Like Growth Factor IReceptor, IGF Type 1Insulin-like growth factor type-1insulin-like growth factor type-1 receptorintrauterine discordancypostnatal growthsmall for gestational age

Identifiers

PMID30859796
PMCPMC6745462
OpenAlexW2922493173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.