ArticleJournal of magnetic resonance imaging : JMRI2019
Measuring tissue sodium concentration: Cross-vendor repeatability and reproducibility of
Article in Journal of magnetic resonance imaging : JMRI, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Variability by region and method in human brain sodium concentrations estimated byScientific reports · 2023Pooled it
- Quantification of the Tissue Sodium Concentration in the Human Calf at 7T With Reduced Acquisition Time: Influence of the Nominal Spatial Resolution.NMR in biomedicine · 2026Article
- Mapping Regional Brain Total Sodium Concentration Using Anatomically Guided Reconstruction of Dual-Echo Sodium-23 MRI: Moving toward Improved Accuracy and Precision.AJNR. American journal of neuroradiology · 2026Article
- Hardware and Software Setup for QuantitativeSensors (Basel, Switzerland) · 2024Article
- The use of sodium MRI in the diagnosis of an anaplastic astrocytoma during immunotherapy: a case report.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Clinically feasible BNMR in biomedicine · 2023Article
- Repeatability of simultaneous 3DScientific reports · 2022Article
- Quantitative Sodium (Diagnostics (Basel, Switzerland) · 2022Article
- Detection of early changes in the post-radiosurgery vestibular schwannoma microenvironment using multinuclear MRI.Scientific reports · 2021Article
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Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundSodium MRI ( PURPOSE: To evaluate the repeatability and reproducibility of TSC measurements in the brains of healthy volunteers, providing evidence for the technical validation of STUDY TYPE: Prospective multicenter study. SUBJECTS: Eleven volunteers (32 ± 6 years; eight males, three females) were scanned twice at each of two sites. FIELD STRENGTH/SEQUENCE: Comparable 3D-cones ASSESSMENT: TSC values, quantified from calibration phantoms placed in the field of view, were obtained from white matter (WM), gray matter (GM), and cerebrospinal fluid (CSF), based on automated segmentation of coregistered STATISTICAL TESTS: Coefficients of variation (CoVs) from mean TSC values were used to assess intrasite repeatability and intersite reproducibility.
resultsMean GM TSC concentrations (52.1 ± 7.1 mM) were ∼20% higher than for WM (41.8 ± 6.7 mM). Measurements were highly repeatable at both sites with mean scan-rescan CoVs between volunteers and regions of 2% and 4%, respectively. Mean intersite reproducibility CoVs were 3%, 3%, and 6% for WM, GM, and CSF, respectively. DATA
conclusionThese results demonstrate technical validation of sodium MRI-derived biomarkers in healthy volunteers. We also show that comparable LEVEL OF EVIDENCE: 1 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2019;50:1278-1284.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.