Evidence map›Paper›PMID 30859432›Full record

Observational studyEuropean journal of nuclear medicine and molecular imaging2019

TSH suppression aggravates arterial inflammation - an

Ellen Boswijk, Karin J C Sanders, Evie P M Broeders, Marlies de Ligt, Guy H E J Vijgen, Bas Havekes, Alma M A Mingels, Roel Wierts, Wouter D van Marken Lichtenbelt, Patrick Schrauwen and 3 more

Open access · hybridAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in European journal of nuclear medicine and molecular imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Enhanced vascular inflammation in patients with advanced prostate cancer receiving hormone therapy.European journal of nuclear medicine and molecular imaging · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Influence of Umbilical Cord Blood Biochemical Parameters and Disease Condition on the Expression of the TSG-6 Gene in Umbilical Mesenchymal Stem Cells.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Article
  7. Article
  8. Observational
  9. American journal of nuclear medicine and molecular imaging · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Ellen BoswijkDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Centre (MUMC+), P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands.
Karin J C SandersDepartment of Nutrition and Movement Sciences, School of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands.
Evie P M BroedersDepartment of Family Medicine, Amsterdam University Medical Centre (Amsterdam UMC), Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands.
Marlies de LigtDepartment of Nutrition and Movement Sciences, School of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands.
Guy H E J VijgenDepartment of Surgery, Franciscus, Kleiweg 500, 3045 PM, Rotterdam, The Netherlands.
Bas HavekesDepartment of Internal Medicine, Division of Endocrinology, Maastricht University Medical Centre (MUMC+), P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands.
Alma M A MingelsDepartment of Clinical Chemistry, Central Diagnostic Laboratory, Maastricht University Medical Centre (MUMC+), P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands.
Roel WiertsDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Centre (MUMC+), P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands.
Wouter D van Marken LichtenbeltDepartment of Nutrition and Movement Sciences, School of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands.
Patrick SchrauwenDepartment of Nutrition and Movement Sciences, School of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands.
Felix M MottaghyDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Centre (MUMC+), P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands.
Joachim E WildbergerDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Centre (MUMC+), P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands.
Jan BuceriusDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Centre (MUMC+), P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands. jan.bucerius@mumc.nl.
Maastricht University Medical Centre · NLMaastricht University · NLRWTH Aachen University · DESint Franciscus Gasthuis · NLUniversity of Amsterdam · NL

Funding

Stichting De Weijerhorst Cardiovasculaire Beeldvorming
6 · The paper itself

Abstract

purposeWe aimed to investigate the influence of both hypothyroidism and thyroid-stimulating hormone (TSH) suppression on vascular inflammation, as assessed with

methodsTen thyroid carcinoma patients underwent an

resultsIn general, there was a trend towards higher vascular TBRs during TSH suppression than during hypothyroidism (TBR

conclusionsArterial inflammation is increased during TSH suppression. This finding sheds new light on the underlying mechanism of the suspected increased risk of cardiovascular disease in patients with TSH suppression.

Indexed as

Positron Emission Tomography Computed TomographyAdultAgedArteritisC-Reactive ProteinFemaleFluorodeoxyglucose F18HumansHypothyroidismInflammationIodine RadioisotopesMaleMiddle AgedProspective StudiesRadiopharmaceuticalsThyroidectomyC-Reactive ProteinFluorodeoxyglucose F18Iodine-131Iodine RadioisotopesRadiopharmaceuticalsThyrotropinThyroxineAtherosclerosisInflammationPositron emission tomography (PET)Thyroid diseaseTSH suppression

Identifiers

PMID30859432
PMCPMC6533218
OpenAlexW2921389418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.