Evidence map›Paper›PMID 30859422›Full record

SynthesisJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2019

Is the Enhanced Recovery After Surgery (ERAS) Program Effective and Safe in Laparoscopic Colorectal Cancer Surgery? A Meta-Analysis of Randomized Controlled Trials.

Xiaofei Ni, Dan Jia, Yan Chen, Lei Wang, Jian Suo

2 registry-linked trialsAbstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 90 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04110080 naunknown statusnot on this map

Enhanced Recovery After Surgery in Living Donor Kidney Transplant Donors

TypeinterventionalSponsorThomas Jefferson UniversityRan2019 to 2023Enrolled42ConditionsOpioid Use, Kidney Diseases, Pain, Postoperative, Postoperative ComplicationsArmsmultimodal pain management, goal directed fluid management, preoperative carbohydrate loading, Donor nephrectomy, regional anesthesia
NCT04159363 naunknown statusnot on this mapstarted 2020, after this paper: background citation

The Effectiveness of an Interactive Colorectal Cancer Self-Management Enhancement Smartphone-based Psychosocial Intervention Programme (iCanManage) on Outcomes of Patients With Colorectal Cancer and Their Family Caregivers

TypeinterventionalSponsorSingapore Cancer SocietyRan2020 to 2021Enrolled200ConditionsColorectal CancerArmsAn interactive Colorectal Cancer self-Management enhancement smartphone-based psychosocial intervention programme (iCanManage)
3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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  8. [Enhanced recovery after surgery-Does the ERAS concept keep its promises].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021
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30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiaofei NiDepartment of Gastrointestinal Surgery, First Hospital of Jilin University, 71Xinmin Street, Chaoyang District, Changchun, 130021, Jilin Province, China.
Dan JiaDepartment of Third Operation Room, First Hospital of Jilin University, 71Xinmin Street, Chaoyang District, Changchun, Jilin Province, China.
Yan ChenDepartment of Gastrointestinal Surgery, First Hospital of Jilin University, 71Xinmin Street, Chaoyang District, Changchun, 130021, Jilin Province, China.
Lei WangDepartment of Gastrointestinal Surgery, First Hospital of Jilin University, 71Xinmin Street, Chaoyang District, Changchun, 130021, Jilin Province, China.
Jian SuoDepartment of Gastrointestinal Surgery, First Hospital of Jilin University, 71Xinmin Street, Chaoyang District, Changchun, 130021, Jilin Province, China. suojian24@hotmail.com.ORCID 0000-0002-0323-4262

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnhanced recovery after surgery (ERAS) program has shown a few advantages in colorectal cancer surgery. However, the effectiveness of the ERAS program in laparoscopic colorectal cancer surgery is still unclear. We performed a meta-analysis of randomized controlled trials (RCTs) to evaluate the effect of ERAS program in laparoscopic colorectal cancer surgery compared with traditional perioperative care (TC).

methodsPubMed, EMBASE, Web of Science, The Cochrane Library, and ClinicalTrials.gov were searched for eligible RCTs comparing ERAS program with TC in laparoscopic colorectal cancer surgery. The main outcomes included the average length of postoperative hospital stay (PHS), time to first flatus and defecation, overall complication, readmission, and mortality rates were undertaken.

resultsThirteen RCTs involving 1298 patients were included in our study (639 in ERAS group and 659 in TC group). ERAS group had shorter average length of PHS (weighted mean difference [WMD] - 2.00 day, 95% confidence interval [CI] - 2.52 to - 1.48, p = 0.00), time to first flatus (WMD - 12.18 h, 95%CI - 16.69 to - 7.67, p = 0.00), and time to first defecation (WMD - 32.93 h, 95%CI - 45.36 to - 20.50, p = 0.00) than TC group. In addition, the overall complication rates (risk ratio [RR] 0.59, 95%CI 0.40 to 0.86, p < 0.01) were significantly lower in ERAS group compared with TC group.

conclusionsThe results indicated that ERAS program is a much better effective and safe protocol for laparoscopic colorectal cancer surgery compared with TC. Hence, ERAS program should be recommended in laparoscopic colorectal cancer surgery.

Indexed as

Enhanced Recovery After SurgeryLaparoscopyColorectal NeoplasmsDefecationHumansLength of StayPatient ReadmissionPerioperative CarePostoperative ComplicationsPostoperative PeriodRandomized Controlled Trials as TopicRecovery of FunctionColorectal cancerEnhanced recovery after surgeryLaparoscopic surgeryMeta-analysis

Identifiers

PMID30859422

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.