Evidence map›Paper›PMID 30859323›Full record

ReviewCurrent allergy and asthma reports2019

BAT in the Diagnosis of Drug Allergy: a Novel Tool in Clinical Daily Practice?

Lucila Campos, Violeta Régnier Galvão, Jorge Kalil, Mariana Castells, Pedro Giavina-Bianchi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current allergy and asthma reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Tools for Etiologic Diagnosis of Drug-Induced Allergic Conditions.International journal of molecular sciences · 2023
    Review
  3. Utilizing Biologics in Drug Desensitization.Current allergy and asthma reports · 2023
    Review
  4. Perioperative Anaphylaxis: Evaluation and Management.Clinical reviews in allergy & immunology · 2022
    Review
  5. Article
  6. Clinical value ofAsia Pacific allergy · 2020
    Review
  7. Pharmacovigilance through Clinical Observation: Case Series of Drug-Related Oral Lesions and Reactions.Nigerian medical journal : journal of the Nigeria Medical Association
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Lucila CamposClinical Immunology and Allergy Division, University of São Paulo, R. Prof. Artur Ramos 178 ap.211A, Jd. América, São Paulo, SP, CEP: 01454-904, Brazil. lucila.campos@uol.com.br.
Violeta Régnier GalvãoClinical Immunology and Allergy Division, University of São Paulo, R. Prof. Artur Ramos 178 ap.211A, Jd. América, São Paulo, SP, CEP: 01454-904, Brazil.
Jorge KalilClinical Immunology and Allergy Division, University of São Paulo, R. Prof. Artur Ramos 178 ap.211A, Jd. América, São Paulo, SP, CEP: 01454-904, Brazil.
Mariana CastellsHarvard medical School, Boston, MA, USA.
Pedro Giavina-BianchiClinical Immunology and Allergy Division, University of São Paulo, R. Prof. Artur Ramos 178 ap.211A, Jd. América, São Paulo, SP, CEP: 01454-904, Brazil.
Universidade de São Paulo · BRHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe aim of this study is to critically review the relevant literature published on basophil activation test, presenting the current knowledge and future perspectives. RECENT

findingsBasophil activation test (BAT) results varied accordingly to the class of the drug studied, and have promising results in immediate hypersensitivity reactions to pyrazolone (selective reactors), neuromuscular blockers, beta-lactams, and platinum compounds, all examples of classical IgE-mediated hypersensitivity drug reactions. Currently, BAT is applied in research settings, but based in the results of our review, the test can be considered as a diagnostic tool for daily practice for selected patients and selected drugs, when the test is available, particularly for patients who experienced severe reactions and when diagnosis cannot be stablished by serum-specific IgE and skin testing, in order to avoid unnecessary drug provocations tests.

Indexed as

Basophil Degranulation TestAnti-Inflammatory Agents, Non-SteroidalBasophilsbeta-LactamsDrug HypersensitivityHumansHypersensitivity, ImmediateNeuromuscular AgentsPyrazolonesAnti-Inflammatory Agents, Non-Steroidalbeta-LactamsNeuromuscular AgentspyrazolonePyrazolonesBasophil activation testBATDrug allergyHypersensitivity reactions

Identifiers

PMID30859323
OpenAlexW2921029738

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.