Evidence map›Paper›PMID 30859112›Full record

ArticleMolecular therapy. Methods & clinical development2019

Novel Diagnostic Tool for p47

Dominik Wrona, Ulrich Siler, Janine Reichenbach

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy. Methods & clinical development, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Reliable genetic diagnosis ofFrontiers in immunology · 2025
    Article
  2. Article
  3. Article
  4. CRISPR-Directed Therapeutic Correction at theMolecular therapy. Methods & clinical development · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Dominik WronaDivision of Immunology, University Children's Hospital Zurich, 8032 Zurich, Switzerland.
Ulrich SilerDivision of Immunology, University Children's Hospital Zurich, 8032 Zurich, Switzerland.
Janine ReichenbachDivision of Immunology, University Children's Hospital Zurich, 8032 Zurich, Switzerland.
Swiss Institute for Regenerative Medicine · CHUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic granulomatous disease (CGD) is a primary immunodeficiency caused by mutations of the phagocytic nicotinamide adenine dinucleotide phosphate (NADPH) oxidase. Autosomal recessive p47

Indexed as

CGDchronic granulomatous diseasegenetic diagnosticsNCF1NCF1BNCF1Cpseudogene

Identifiers

PMID30859112
PMCPMC6395829
OpenAlexW2914929031

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.