ArticleCurrent otorhinolaryngology reports2018
Understanding the Role of Biofilms and Superantigens in Chronic Rhinosinusitis.
Article in Current otorhinolaryngology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 41 citations in OpenAlex.
- A ROS-responsive nanozyme delivering gallic acid synergistically ameliorates chronic rhinosinusitis via epithelial barrier restoration and Syk/NF-κB inhibition.International journal of pharmaceutics: X · 2026Article
- The infectome framework: linking polymicrobial ecology and biofilm dynamics to precision diagnostic approaches.Infection · 2026Review
- Antibiofilm Effects of N-Acetyl Cysteine on Staphylococcal Biofilm in Patients with Chronic Rhinosinusitis.Microorganisms · 2025Article
- The pediatric nasal microbiome and its role in chronic ENT disorders: a narrative review.Frontiers in immunology · 2025Review
- Mupirocin Ointment Effect on Polyposis Recurrence After Sinus Surgery.Iranian journal of otorhinolaryngology · 2024Article
- Expert consensus on odontogenic maxillary sinusitis multi-disciplinary treatment.International journal of oral science · 2024Review
- BIOFILM AND HISTOPATHOLOGICAL GRADING OF MAXILLARY SINUS MUCOSA IN PATIENTS WITH ANTROCHOANAL POLYPS.Acta clinica Croatica · 2023Article
- Matrix-Mediated Delivery of Silver Nanoparticles for Prevention ofPharmaceutics · 2023Article
- Type 2 chronic inflammatory diseases: targets, therapies and unmet needs.Nature reviews. Drug discovery · 2023Review
- The Mechanism of Action and Clinical Efficacy of Low-Dose Long-Term Macrolide Therapy in Chronic Rhinosinusitis.International journal of molecular sciences · 2023Review
- Article
- Chronic rhinosinusitis: Future treatments and unmet needs.The Journal of allergy and clinical immunology · 2022Article
- Odontogenic Sinusitis: From Diagnosis to Treatment Possibilities-A Narrative Review of Recent Data.Diagnostics (Basel, Switzerland) · 2022Review
- Revisiting the controversy: The role of fungi in chronic rhinosinusitis.International forum of allergy & rhinology · 2021Review
- Sinonasal Stent Coated with Slow-Release Varnish of Chlorhexidine Has Sustained Protection against Bacterial Biofilm Growth in the Sinonasal Cavity: An In Vitro Study.Pharmaceutics · 2021Article
- Current Perspective on Nasal Delivery Systems for Chronic Rhinosinusitis.Pharmaceutics · 2021Review
- Expression of Transcript Variants ofDiagnostics (Basel, Switzerland) · 2021Article
- Antibiofilm peptides: overcoming biofilm-related treatment failure.RSC advances · 2021Review
- Biofilm and Planktonic Antibiotic Resistance in Patients With Acute Exacerbation of Chronic Rhinosinusitis.Frontiers in cellular and infection microbiology · 2021Article
- Bacterial Biofilm and its Role in the Pathogenesis of Disease.Antibiotics (Basel, Switzerland) · 2020Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
purpose of reviewThis review explores recent discoveries in our understanding of how biofilms and superantigens contribute to the pathogenesis of chronic rhinosinusitis (CRS). It also examines clinical implications and novel treatment approaches for biofilm associated CRS. RECENT
findingsWhile the role of biofilms in CRS has been studied for 14 years, research interest has now turned toward elucidating new methods of biofilm detection, microbial diversity, and novel treatment approaches. Recent studies on biofilm superantigens aim to clarify the immunological mechanisms of upper airway inflammation, particularly the type-2 response seen in nasal polyposis. SUMMARY: Biofilms are a topic of research interest for their role in the pathogenesis of chronic rhinosinusitis, particularly when they elute superantigens. New studies on this topic focus on the molecular and cellular mechanisms at play.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.