ArticleMediterranean journal of hematology and infectious diseases2019
Can Base Excess be Used for Prediction to Early Diagnosis of Neonatal Sepsis in Preterm Newborns?
Article in Mediterranean journal of hematology and infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Clinical characteristics and outcomes of congenital diaphragmatic hernia (CDH) in neonates in an Australian neonatal intensive care unit network: a population-based cohort study.BMJ paediatrics open · 2026Article
- The predictive values of admission characteristics for 28-day all-cause mortality in septic patients with diabetes mellitus: a study from the MIMIC database.Frontiers in endocrinology · 2023Article
- Methylene Blue to Neonatal Septic Shock treatment in neonate pigsClinics (Sao Paulo, Brazil) · 2022Article
- Diagnostic Accuracy of Clinical Tool 'STOPS' and Serum Procalcitonin for Optimizing Antibiotic Therapy in Neonates Born at ≥ 28 Weeks of Gestation with Neonatal Sepsis.Mediterranean journal of hematology and infectious diseases · 2021Article
- Association Between Base Excess and Mortality Among Patients in ICU With Acute Kidney Injury.Frontiers in medicine · 2021Article
- Mortality Prediction of Septic Patients in the Emergency Department Based on Machine Learning.Journal of clinical medicine · 2019Article
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6 authors.
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Abstract
backgroundNeonatal sepsis remains an important and potentially life-threatening clinical syndrome and a major cause of neonatal mortality and morbidity. The aim of this study to investigate whether values of base excess before the onset of clinical signs and symptoms of sepsis indicate infection in the early diagnosis of neonatal sepsis.
methodsIn this study, a total of 118 infants were enrolled. The infants were classified into two groups: group 1 (sepsis, n=49) and group 2 (control, n=69). Blood gas analysis investigated for the screening of neonatal sepsis.
resultsA total of 49 newborns with neonatal sepsis and 69 healthy controls were enrolled. Comparison of markers of sepsis revealed C-reactive protein, interleukin-6 level to be significantly higher and pH, pCO
conclusionThis is the first study to determine the relationship between the decreased value of the base excess and early stage of neonatal sepsis. If the value of base excess <-5 mmol/L without an underlying another reason, may need close follow up of infants for neonatal sepsis and it may help early diagnosis.
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