ReviewInterventional cardiology (London, England)2019
Patent Foramen Ovale Closure in 2019.
Review in Interventional cardiology (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 0 citations in OpenAlex.
- Trial
- Exercise-Induced Desaturation in Patent Foramen Ovale: Mechanisms, Diagnostic Approach, and Resolution After Closure-A Narrative Review with an Illustrative Case.Journal of clinical medicine · 2026Review
- Long-term incidence of first hospital-recorded atrial arrhythmias and all-cause mortality after percutaneous patent foramen ovale closure: a single-centre cohort linked to Czech nationwide administrative health data.Frontiers in cardiovascular medicine · 2026Article
- The safety, efficacy, and influencing factors of biodegradable versus metallic occluders in the treatment of migraine patients with patent foramen ovale.Frontiers in neurology · 2025Article
- A preserved transseptal puncture zone in a novel PFO occluder enables safe repeat left atrial interventions: preclinical validation in a porcine model.Frontiers in cardiovascular medicine · 2025Article
- Article
- Review
- Transesophageal echocardiography guidance for percutaneous closure of PFO and a new method to improve the diagnosis and safety during the procedures.Frontiers in cardiovascular medicine · 2024Article
- Cryptogenic Stroke Caused by a Newly Diagnosed Patent Foramen Ovale in a Healthy Young Adult.Cureus · 2023Article
- Transesophageal echocardiography-guided percutaneous closure of the patent foramen ovale only uses the sheath.Cardiovascular diagnosis and therapy · 2023Article
- Coexistence of right-to-left and left-to-right shunts across patent foramen ovale and coronary cameral fistulas.Journal of cardiology cases · 2023Article
- Synchronous multimode ultrasound for assessing right-to-left shunt: a prospective clinical study.Frontiers in neurology · 2023Article
- Exertional desaturations after COVID-19: A case for PFO closure.Echocardiography (Mount Kisco, N.Y.) · 2022Article
- Patent foramen ovale: diagnostic evaluation and the role of device closure.Clinical medicine (London, England) · 2022Review
- Developing a random forest algorithm to identify patent foramen ovale and atrial septal defects in Ontario administrative databases.BMC medical informatics and decision making · 2022Article
- Stroke and presence of patent foramen ovale in sickle cell disease.Journal of thrombosis and thrombolysis · 2021Review
- Thrombus in transit through a patent foramen ovale: catch it if you can-a case report.European heart journal. Case reports · 2021Article
- Patient with systemic emboli in the setting ofBMJ case reports · 2021Article
- The correlation between patent foramen ovale and brain ischemia in plateau residents.BMC cardiovascular disorders · 2021Article
- Platypnea and orthodeoxia syndrome as an uncommon clinical indication for a challenging percutaneous patent foramen ovale closure: a case report.European heart journal. Case reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patent foramen ovale (PFO) is a common abnormality affecting between 20% and 34% of the adult population. For most people it is a benign finding; however, in some the PFO can open widely, enabling a paradoxical embolus to transit from the venous to arterial circulation, which is associated with stroke and systemic embolisation. Percutaneous closure of PFO in patients with cryptogenic stroke has been undertaken for a number of years, and a number of purpose-specific septal occluders have been marketed. Recent randomised controlled trials have demonstrated that closure of PFO in patients with cryptogenic stroke is associated with reduced rates of recurrent stroke. After a brief overview of the anatomy of a PFO, this review considers the evidence for PFO closure in cryptogenic stroke. The review also addresses other potential indications for closure, including systemic embolisation, decompression sickness, platypnoea-orthodeoxia syndrome and migraine with aura. It lays out the pre-procedural investigations and preparation for the procedure. Finally, it gives an overview of the procedure itself, including discussion of closure devices.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.