ArticleBiotechnology for biofuels2019
Polysaccharide monooxygenase-catalyzed oxidation of cellulose to glucuronic acid-containing cello-oligosaccharides.
Article in Biotechnology for biofuels, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 34 citations in OpenAlex.
- Genomic and Functional Analysis of Auxiliary Activity Enzymes in the Maize Anthracnose PathogenMicroorganisms · 2025Article
- Effect of itaconic acid production on Neurospora crassa in consolidated bioprocessing of cellulose.Microbial cell factories · 2023Article
- Oxidative cleavage of cellulose in the horse gut.Microbial cell factories · 2022Article
- Analysis of lytic polysaccharide monooxygenase activity in thermophilic fungi by high-performance liquid chromatography-refractive index detector.Frontiers in microbiology · 2022Article
- Insights into the genome and secretome of Fusarium metavorans DSM105788 by cultivation on agro-residual biomass and synthetic nutrient sources.Biotechnology for biofuels · 2021Article
- Biochemical Characterization of a Bifunctional Enzyme Constructed by the Fusion of a Glucuronan Lyase and a Chitinase fromLife (Basel, Switzerland) · 2020Article
- Functional characterization of cellulose-degrading AA9 lytic polysaccharide monooxygenases and their potential exploitation.Applied microbiology and biotechnology · 2020Review
- Glucose-Mediated Repression of Plant Biomass Utilization in the White-Rot FungusApplied and environmental microbiology · 2019Article
- Metabolomic profiling of oxalate-degrading probiotic Lactobacillus acidophilus and Lactobacillus gasseri.PloS one · 2019Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPolysaccharide monooxygenases (PMOs) play an important role in the enzymatic degradation of cellulose. They have been demonstrated to able to C6-oxidize cellulose to produce C6-hexodialdoses. However, the biological function of C6 oxidation of PMOs remains unknown. In particular, it is unclear whether C6-hexodialdoses can be further oxidized to uronic acid (glucuronic acid-containing oligosaccharides).
resultsA PMO gene,
conclusionsHiPMO1 oxidizes C6 of cellulose to form glucuronic acid-containing cello-oligosaccharides followed by hydrolysis with beta-glucosidase and beta-glucuronidase to yield glucose, glucuronic acid, and saccharic acid, and even possibly by beta-eliminative cleavage to produce unsaturated cello-oligosaccharides. This study provides a new mechanism for cellulose cleavage by C6 oxidation of HiPMO1.
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