Evidence map›Paper›PMID 30858847›Full record

ArticleFrontiers in immunology2019

Elevated Systemic Pentraxin-3 Is Associated With Complement Consumption in the Acute Phase of Thrombotic Microangiopathies.

Eszter Trojnar, Mihály Józsi, Zsóka Szabó, Marienn Réti, Péter Farkas, Kata Kelen, George S Reusz, Attila J Szabó, Nóra Garam, Bálint Mikes and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Eszter TrojnarResearch Laboratory, MTA-SE Research Group of Immunology and Hematology, 3rd Department of Internal Medicine, Hungarian Academy of Sciences and Semmelweis University, Budapest, Hungary.
Mihály JózsiComplement Research Group, Department of Immunology, ELTE Eötvös Loránd University, Budapest, Hungary.
Zsóka SzabóComplement Research Group, Department of Immunology, ELTE Eötvös Loránd University, Budapest, Hungary.
Marienn RétiDepartment of Haematology and Stem Cell Transplantation, Central Hospital of Southern Pest, National Institute for Hematology and Infectious Diseases, Budapest, Hungary.
Péter FarkasResearch Laboratory, MTA-SE Research Group of Immunology and Hematology, 3rd Department of Internal Medicine, Hungarian Academy of Sciences and Semmelweis University, Budapest, Hungary.
Kata Kelen1st Department of Pediatrics, Semmelweis University, Budapest, Hungary.
George S Reusz1st Department of Pediatrics, Semmelweis University, Budapest, Hungary.
Attila J Szabó1st Department of Pediatrics, Semmelweis University, Budapest, Hungary.
Nóra GaramResearch Laboratory, MTA-SE Research Group of Immunology and Hematology, 3rd Department of Internal Medicine, Hungarian Academy of Sciences and Semmelweis University, Budapest, Hungary.
Bálint MikesResearch Laboratory, MTA-SE Research Group of Immunology and Hematology, 3rd Department of Internal Medicine, Hungarian Academy of Sciences and Semmelweis University, Budapest, Hungary.
György SinkovitsResearch Laboratory, MTA-SE Research Group of Immunology and Hematology, 3rd Department of Internal Medicine, Hungarian Academy of Sciences and Semmelweis University, Budapest, Hungary.
Blanka MezőResearch Laboratory, MTA-SE Research Group of Immunology and Hematology, 3rd Department of Internal Medicine, Hungarian Academy of Sciences and Semmelweis University, Budapest, Hungary.
Dorottya CsukaResearch Laboratory, MTA-SE Research Group of Immunology and Hematology, 3rd Department of Internal Medicine, Hungarian Academy of Sciences and Semmelweis University, Budapest, Hungary.
Zoltán ProhászkaResearch Laboratory, MTA-SE Research Group of Immunology and Hematology, 3rd Department of Internal Medicine, Hungarian Academy of Sciences and Semmelweis University, Budapest, Hungary.
Semmelweis University · HUHungarian Academy of Sciences · HUEötvös Loránd University · HUNational Center for Epidemiology · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pentraxin-3 (PTX3) and C-reactive protein (CRP) have been shown to regulate complement activation

Indexed as

Complement ActivationAdolescentAdultAtypical Hemolytic Uremic SyndromeChildComplement Pathway, AlternativeC-Reactive ProteinFemaleHumansMaleMiddle AgedPentraxinsPurpura, Thrombotic ThrombocytopenicSerum Amyloid P-ComponentThrombotic MicroangiopathiesYoung AdultC-Reactive ProteinPentraxinsSerum Amyloid P-Componentalternative pathwaycomplement consumptionC-reactive proteinhemolytic uremic syndromepentraxin-3thrombotic microangiopathiesthrombotic thrombocytopenic purpura

Identifiers

PMID30858847
PMCPMC6397851
OpenAlexW2915525416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.