Evidence map›Paper›PMID 30858840›Full record

ArticleFrontiers in microbiology2019

Hexokinase and Glucokinases Are Essential for Fitness and Virulence in the Pathogenic Yeast

Romain Laurian, Karine Dementhon, Bastien Doumèche, Alexandre Soulard, Thierry Noel, Marc Lemaire, Pascale Cotton

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Journal of bacteriology · 2026
    Article
  3. Article
  4. DVL, a Lectin fromAntibiotics (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Microorganisms · 2021
    Article
  11. Lineage-specific selection and the evolution of virulence in theProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  12. Article
  13. Moonlighting Proteins: The Case of the Hexokinases.Frontiers in molecular biosciences · 2021
    Review
  14. Article
  15. Mechanism of Candida pathogenesis: revisiting the vital drivers.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
    Review
  16. New Insights inFrontiers in cellular and infection microbiology · 2020
    Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Romain LaurianGénétique Moléculaire des Levures, UMR-CNRS 5240 Microbiologie Adaptation et Pathogénie, Université de Lyon - Université Lyon 1, Lyon, France.
Karine DementhonLaboratoire de Microbiologie Fondamentale et Pathogénicité, UMR-CNRS 5234, Université de Bordeaux, Bordeaux, France.
Bastien DoumècheInstitut de Chimie et Biochimie Moléculaires et Supramoléculaires, Université de Lyon - Université Lyon 1, Lyon, France.
Alexandre SoulardGénétique Moléculaire des Levures, UMR-CNRS 5240 Microbiologie Adaptation et Pathogénie, Université de Lyon - Université Lyon 1, Lyon, France.
Thierry NoelLaboratoire de Microbiologie Fondamentale et Pathogénicité, UMR-CNRS 5234, Université de Bordeaux, Bordeaux, France.
Marc LemaireGénétique Moléculaire des Levures, UMR-CNRS 5240 Microbiologie Adaptation et Pathogénie, Université de Lyon - Université Lyon 1, Lyon, France.
Pascale CottonGénétique Moléculaire des Levures, UMR-CNRS 5240 Microbiologie Adaptation et Pathogénie, Université de Lyon - Université Lyon 1, Lyon, France.
Laboratoire de Microbiologie, Adaptation et Pathogénie · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pathogenic yeast

Indexed as

Candida albicansglucokinaseglucose repressionglycolysishexokinasehyphal transitionvirulence

Identifiers

PMID30858840
PMCPMC6401654
OpenAlexW2949635797

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.