Evidence map›Paper›PMID 30858770›Full record

ArticleDose-response : a publication of International Hormesis Society

Impact of

Ryo Toya, Tetsuo Saito, Yudai Kai, Shinya Shiraishi, Tomohiko Matsuyama, Takahiro Watakabe, Fumi Sakamoto, Noriko Tsuda, Yoshinobu Shimohigashi, Yasuyuki Yamashita and 1 more

Open access · goldAbstract read
In one paragraph

Article in Dose-response : a publication of International Hormesis Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Radiological physics and technology · 2026
    Article
  3. Article
  4. Article
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  9. Proteomic Analysis of Radiation-Induced Acute Liver Damage in a Rabbit Model.Dose-response : a publication of International Hormesis Society
    Article
  10. Implementation ofIn vivo (Athens, Greece)
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Ryo ToyaDepartment of Radiation Oncology, Kumamoto University Hospital, Kumamoto, Japan.ORCID https://orcid.org/0000-0001-9764-5718
Tetsuo SaitoDepartment of Radiation Oncology, Kumamoto University Hospital, Kumamoto, Japan.
Yudai KaiDepartment of Radiological Technology, Kumamoto University Hospital, Kumamoto, Japan.
Shinya ShiraishiDepartment of Diagnostic Radiology, Kumamoto University Hospital, Kumamoto, Japan.
Tomohiko MatsuyamaDepartment of Radiation Oncology, Kumamoto University Hospital, Kumamoto, Japan.
Takahiro WatakabeDepartment of Radiation Oncology, Kumamoto University Hospital, Kumamoto, Japan.
Fumi SakamotoDepartment of Diagnostic Radiology, Kumamoto University Hospital, Kumamoto, Japan.
Noriko TsudaDepartment of Diagnostic Radiology, Kumamoto University Hospital, Kumamoto, Japan.
Yoshinobu ShimohigashiDepartment of Radiological Technology, Kumamoto University Hospital, Kumamoto, Japan.
Yasuyuki YamashitaDepartment of Diagnostic Radiology, Kumamoto University Hospital, Kumamoto, Japan.
Natsuo OyaDepartment of Radiation Oncology, Kumamoto University Hospital, Kumamoto, Japan.
Kumamoto University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the impact of

methodsEleven patients were enrolled in this study. The functional liver structure (FLS) was derived from SPECT thresholds of 60% to 80% of the maximum pixel value. Two treatment plans optimized without FLS (plan C) and with FLS (plan F) were designed for 50 Gy to the planning target volume (PTV). The DFH parameters were calculated as follows:

resultsCompared with plan C, plan F significantly reduced DFH parameters of F

conclusionDFH analyses revealed that

Indexed as

dose–function histogramdose–volume histogramhepatocellular carcinomamolecular imagingradiation-induced liver diseasestereotactic body radiation therapy

Identifiers

PMID30858770
PMCPMC6402061
OpenAlexW2919119343

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.