ArticleScientific reports2019
Enzymatic origin and various curvatures of metabolic scaling in microbes.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- The metabolic rate of the biosphere and its components.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Simple Growth-Metabolism Relations Are Revealed by Conserved Patterns of Heat Flow from Cultured Microorganisms.Microorganisms · 2022Article
- A Revision of the Traditional Analysis Method of Allometry to Allow Extension of the Normality-Borne Complexity of Error Structure: Examining the Adequacy of a Normal-Mixture Distribution-Driven Error Term.BioMed research international · 2022Article
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2 authors.
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Abstract
The famous and controversial power law is a basal metabolic scaling model mainly derived from the "surface rule" or a fractal transport network. However, this law neglects biological mechanisms in the important active state. Here, we hypothesized that the relative metabolic rate and growth rate of actively growing microbes are driven by the changeable rate of their rate-limiting enzymes and concluded that natural logarithmic microbial metabolism (lnλ) and growth (or biomass) (lnM) are both dependent on limiting resources, and then developed novel models with interdependence between lnλ and lnM. We tested the models using the data obtained from the literature. We explain how and why the scaling is usually curved with the difference between microbial metabolic and growth (or biomass's) half-saturation constants (K
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