Evidence map›Paper›PMID 30858359›Full record

ArticleBlood cancer journal2019

Genomic analyses of microdissected Hodgkin and Reed-Sternberg cells: mutations in epigenetic regulators and p53 are frequent in refractory classic Hodgkin lymphoma.

Elena Mata, Sara Fernández, Aurora Astudillo, Rubén Fernández, Mónica García-Cosío, Margarita Sánchez-Beato, Mariano Provencio, Mónica Estévez, Carlos Montalbán, Miguel A Piris and 1 more

Open access · goldAbstract readLetter
In one paragraph

Article in Blood cancer journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. A genetic profiling guideline to support diagnosis and clinical management of lymphomas.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
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  15. Can we use epigenetics to prime chemoresistant lymphomas?Hematology. American Society of Hematology. Education Program · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Elena MataDepartments of Pathology, MD Anderson Cancer Center Madrid, Madrid, Spain.
Sara FernándezDepartments of Pathology, MD Anderson Cancer Center Madrid, Madrid, Spain.
Aurora AstudilloDepartments of Pathology, Hospital Universitario de Cabueñes, Gijón, Spain.ORCID http://orcid.org/0000-0001-8947-8809
Rubén FernándezDepartments of Hematology, Hospital Universitario de Cabueñes, Gijón, Spain.
Mónica García-CosíoDepartment of Pathology, Hospital Universitario Ramón y Cajal, Madrid, Spain.
Margarita Sánchez-BeatoInstituto Investigación Sanitaria Puerta de Hierro - Segovia de Arana (IDIPHISA), Centro de Investigación Biomédica en Red de Cáncer (CIBERONC) Instituto de Salud Carlos III, Madrid, Spain.
Mariano ProvencioInstituto Investigación Sanitaria Puerta de Hierro - Segovia de Arana (IDIPHISA), Centro de Investigación Biomédica en Red de Cáncer (CIBERONC) Instituto de Salud Carlos III, Madrid, Spain.
Mónica EstévezDepartments of Hematology, MD Anderson Cancer Center Madrid, Madrid, Spain.
Carlos MontalbánDepartments of Hematology, MD Anderson Cancer Center Madrid, Madrid, Spain.
Miguel A PirisDepartment of Pathology, Fundación Jiménez Díaz, Madrid; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC) Instituto de Salud Carlos III, Madrid, Spain.
Juan F GarcíaDepartments of Pathology, MD Anderson Cancer Center Madrid, Madrid, Spain. jfgarcia@mdanderson.es.
MD Anderson Cancer Center Madrid · ESInstituto de Salud Carlos III · ESHospital Universitario De Cabueñes · ESHospital Universitario Ramón y Cajal · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

GenomicsAdultAgedBiomarkers, TumorEpigenesis, GeneticFemaleGene Expression Regulation, NeoplasticGene FrequencyHodgkin DiseaseHumansMaleMicrodissectionMiddle AgedMutationNeoplasm StagingReed-Sternberg CellsBiomarkers, TumorTumor Suppressor Protein p53

Identifiers

PMID30858359
PMCPMC6411728
OpenAlexW2921267178

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.