ArticleProceedings of the National Academy of Sciences of the United States of America2019
Unexpected systemic phenotypes result from focal combined deficiencies of forebrain insulin receptor/IGF-1 receptor signaling.
Sam Gandy, Derek M Huffman
Abstract readComment
In one paragraphArticle in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
2 authors.
Sam GandyThe NFL Neurological Program, Center for Cognitive Health, Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029; samuel.gandy@mssm.edu.
Derek M HuffmanDepartment of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY 10461.
Funding
VESICULAR LOCALIZATION AND FUNCTION OF PRESENILIN 1 FRAGMENTP50AG005138 · NIA · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI GROSSMAN, HILLEL · 1985 to 2019
$37.9MStable Isotope and Metabolomics CoreP60DK020541 · NIDDK · YESHIVA UNIVERSITY · PI PESSIN, JEFFREY E. · 1986 to 2014
$29.8MTranslational Research CoreP30DK020541 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI STREAMSON C CHUA · 2015 to 2026
$27.7MIntegrative Network Biology Approaches to Identify, Characterize and Validate Molecular Subtypes in Alzheimer's DiseaseU01AG046170 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WANG, MINGHUI, ZHANG, BIN · 2013 to 2022
$26.0MEinstein's Nathan Shock Center of Excellence in Basic Biology of AgingP30AG038072 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI VIJG, JAN · 2010 to 2024
$10.8MUse of iPSC systems to define roles of microglial TREM2/DAP12 and CR3/DAP12 complexes and their genetic variants in specifying risk for late onset sporadic Alzheimer's diseaseR01AG061894 · NIA · NEW YORK STEM CELL FOUNDATION · PI FOSSATI, VALENTINA, GANDY, SAMUEL E. · 2018 to 2022
$4.2MIntegrated understanding of complex viral network biology in Alzheimer's DiseaseRF1AG058469 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI EHRLICH, MICHELLE E, GANDY, SAMUEL E. · 2019 to 2019
$4.1MStructural and Functional Neuroimaging of Post Traumatic Stress Disorder and Cognitive Impairment in World Trade Center RespondersU01OH011314 · OH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI LUCCHINI, ROBERTO G, LUFT, BENJAMIN J · 2016 to 2019
$2.4MOptimizing resilience assays for biology of aging research in miceR01AG057429 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI HUFFMAN, DEREK MAJOR · 2017 to 2021
$1.8MIntegrated understanding of complex viral network biology in Alzheimer's DiseaseR56AG058469 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI DUDLEY, JOEL THOMAS, EHRLICH, MICHELLE E · 2017 to 2017
$844kCell autonomous versus non-cell autonomous aging in intestinal decline and tumorigenesisR21AG055026 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI HUFFMAN, DEREK MAJOR · 2017 to 2018
$459kRehab Therapy Adjunct with a Neurogenic, Mnemoactive, A-Beta-Lowering CompoundI01RX000684 · VA · JAMES J PETERS VA MEDICAL CENTER · PI GANDY, SAMUEL E. · 2014 to 2017
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6 · The paper itselfAbstract
PubMed holds no abstract for this paper.
Indexed as
InsulinsAmygdalaHippocampusPhenotypeProsencephalonReceptor, IGF Type 1Receptor, InsulinInsulinsReceptor, IGF Type 1Receptor, Insulin
Identifiers
PMID30858326
PMCPMC6442574
What OpenQuestion holds
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