Evidence map›Paper›PMID 30858308›Full record

ArticleBioscience reports2019

Increased risk of hepatitis B virus infection amongst individuals with diabetes mellitus.

Xuan Zhang, Xia Zhu, Yulin Ji, Hong Li, Fengsu Hou, Chuan Xiao, Ping Yuan

Open access · goldAbstract read
In one paragraph

Article in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 33 citations in OpenAlex.

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  6. [Expert recommendations on screening, testing and management for hepatitis B virus infection in adults].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xuan ZhangDepartment of Epidemiology and Statistics, West China School of Public Health, Sichuan University, Chengdu 610041, Sichuan Province, China.
Xia ZhuCenter of Infectious Disease, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Yulin JiDepartment of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Hong LiDepartment of Urology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Fengsu HouDepartment of Epidemiology and Statistics, West China School of Public Health, Sichuan University, Chengdu 610041, Sichuan Province, China.
Chuan XiaoDepartment of Epidemiology and Statistics, West China School of Public Health, Sichuan University, Chengdu 610041, Sichuan Province, China.
Ping YuanDepartment of Epidemiology and Statistics, West China School of Public Health, Sichuan University, Chengdu 610041, Sichuan Province, China yuanping1117@126.com.ORCID 0000-0003-2027-0510
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There have been reports of hepatitis B outbreaks amongst diabetics in long-term care facilities, suggesting that risk of hepatitis B virus (HBV) infection is higher in this population. However, the magnitude of the risk and the incidence of HBV infection amongst the general diabetic population in China remains unknown. Data from a cohort study conducted in Mianyang City, Sichuan Province, China, were retrospectively analyzed in order to address this question. Demographic information was collected using a custom-designed questionnaire, and blood samples were tested for HBV using ELISA. We used multivariate logistic regression to explore the relationship between HBV infection and diabetes, while adjusting for age, sex, region, medical insurance, exposure history, and HBV vaccination. During 2013-2014, a total of 189766 adults were surveyed, of which 7382 were newly infected with HBV, corresponding to an incidence of 3.89%. In this study population, there were 4982 diabetic patients and 182710 non-diabetic individuals. Amongst those with diabetes, 265 (5.32%) were newly infected with HBV. In contrast, 7038 (3.85%) in the non-diabetic population were newly infected with HBV. The relative risk (RR) of HBV infection was 43% higher amongst those diagnosed with diabetes than amongst those not diagnosed (RR 1.43, 95% confidence interval (CI) 1.26-1.63). These results suggest that the risk of HBV infection is higher amongst individuals diagnosed with diabetes mellitus in Mianyang City, Sichuan Province, China. Hepatitis B vaccination and continuous infection control practices may help to reduce HBV infection in diabetic patients, and should be considered for diabetes management.

Indexed as

AdolescentAdultAgedAged, 80 and overAsian PeopleChinaComorbidityDiabetes MellitusFemaleHealth SurveysHepatitis BHumansIncidenceMaleMiddle AgedRetrospective StudiesBlood glucose monitoringDiabetes mellitusHepatitis B virusPreventionRisk of infection

Identifiers

PMID30858308
PMCPMC6438870
OpenAlexW2921815809

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.