Evidence map›Paper›PMID 30858305›Full record

Trial reportGut2019

Randomised controlled trial of WISENSE, a real-time quality improving system for monitoring blind spots during esophagogastroduodenoscopy.

Lianlian Wu, Jun Zhang, Wei Zhou, Ping An, Lei Shen, Jun Liu, Xiaoda Jiang, Xu Huang, Ganggang Mu, Xinyue Wan and 19 more

2 registry-linked trialsOpen access · bronzeAbstract readRandomized Controlled TrialVideo-Audio Media
In one paragraph

Trial report in Gut, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 132 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
132citing papers in PubMed, 11 pooled it
40.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04203264 unknown statusnot on this map

Real-Time Identification of Gastric Lesions and Anatomical Landmarks During Magnetically Controlled Capsule Endoscopy Using Artificial Intelligence

TypeobservationalSponsorChanghai HospitalRan2019 to 2020Enrolled50ConditionsCapsule EndoscopyArmsReal-time artificial intelligence identification system
NCT05832411 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Effect of Artificial Intelligence Monitoring Blind Spots of EGD on the Inspection Time and Dection Rate of Neoplastic Lesions

TypeinterventionalSponsorRenmin Hospital of Wuhan UniversityRan2023 to 2024Enrolled1,672ConditionsUpper Gastrointestinal SymptomsArmsEndoangle
3 · Its place in the literature

Who cites it

132 citing papers in PubMed, 11 syntheses or guidelines pooled it, 309 citations in OpenAlex.

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  16. Screening strategies for the early detection of non-cardia gastric cancer in low- to moderate-prevalence regions: Asia-Pacific gastroesophageal cancer congress consensus 2026.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026
    Review
  17. Artificial Intelligence for Esophageal Precancerous Lesions and Esophageal Cancer.The Korean journal of helicobacter and upper gastrointestinal research · 2026
    Review
  18. Artificial Intelligence for Endoscopic Diagnosis of Gastric Premalignant Lesions.The Korean journal of helicobacter and upper gastrointestinal research · 2026
    Review
  19. Clinical Performance of Gastric CADe: Beyond Lesion Recognition From the G-CADe Trial.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026
    Article
  20. Review

72 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

29 authors at 1 institution in 1 country.

Lianlian Wu *Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Jun Zhang *Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Wei Zhou *Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Ping AnDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Lei ShenDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Jun LiuDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Xiaoda JiangDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Xu HuangDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Ganggang MuDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Xinyue WanDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.ORCID 0000-0002-4507-2011
Xiaoguang LvDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Juan GaoDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Ning CuiDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Shan HuSchool of Resources and Environmental Sciences of Wuhan University, Wuhan, China.
Yiyun ChenSchool of Resources and Environmental Sciences of Wuhan University, Wuhan, China.
Xiao HuSchool of Resources and Environmental Sciences of Wuhan University, Wuhan, China.
Jiangjie LiSchool of Resources and Environmental Sciences of Wuhan University, Wuhan, China.
Di ChenDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Dexin GongDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Xinqi HeDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Qianshan DingDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Xiaoyun ZhuDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Suqin LiDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Xiao WeiDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Xia LiDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Xuemei WangDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Jie ZhouDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Mengjiao ZhangDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Hong Gang YuDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.ORCID 0000-0002-1882-7060
Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEsophagogastroduodenoscopy (EGD) is the pivotal procedure in the diagnosis of upper gastrointestinal lesions. However, there are significant variations in EGD performance among endoscopists, impairing the discovery rate of gastric cancers and precursor lesions. The aim of this study was to construct a real-time quality improving system, WISENSE, to monitor blind spots, time the procedure and automatically generate photodocumentation during EGD and thus raise the quality of everyday endoscopy.

designWISENSE system was developed using the methods of deep convolutional neural networks and deep reinforcement learning. Patients referred because of health examination, symptoms, surveillance were recruited from Renmin hospital of Wuhan University. Enrolled patients were randomly assigned to groups that underwent EGD with or without the assistance of WISENSE. The primary end point was to ascertain if there was a difference in the rate of blind spots between WISENSE-assisted group and the control group.

resultsWISENSE monitored blind spots with an accuracy of 90.40% in real EGD videos. A total of 324 patients were recruited and randomised. 153 and 150 patients were analysed in the WISENSE and control group, respectively. Blind spot rate was lower in WISENSE group compared with the control (5.86% vs 22.46%, p<0.001), and the mean difference was -15.39% (95% CI -19.23 to -11.54). There was no significant adverse event.

conclusionsWISENSE significantly reduced blind spot rate of EGD procedure and could be used to improve the quality of everyday endoscopy. TRIAL REGISTRATION NUMBER: ChiCTR1800014809; Results.

Indexed as

Quality ImprovementEndoscopy, Digestive SystemFemaleGastrointestinal DiseasesHumansMaleMiddle AgedMonitoring, PhysiologicProspective StudiesSingle-Blind MethodTime FactorsUpper Gastrointestinal Tractendoscopy

Identifiers

PMID30858305
PMCPMC6872441
OpenAlexW2922329578

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.