Evidence map›Paper›PMID 30858300›Full record

ArticleJournal of bacteriology2019

Antibiotic Korormicin A Kills Bacteria by Producing Reactive Oxygen Species.

Adam Maynard, Nicole L Butler, Takeshi Ito, Adilson José da Silva, Masatoshi Murai, Tsute Chen, Mattheos A G Koffas, Hideto Miyoshi, Blanca Barquera

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Quinolone inhibitors targetingEuropean journal of medicinal chemistry reports · 2026
    Article
  3. Conformational Dynamics of NaJournal of chemical information and modeling · 2026
    Article
  4. The redox driven NaNature communications · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Cryo-EM structures of NaNature communications · 2022
    Article
  14. Review
  15. Molecular dynamics modeling of the Vibrio cholera NaMolecular and cellular biochemistry · 2022
    Article
  16. Article
  17. Article
  18. Inhibitors of a NaThe Journal of biological chemistry · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Adam MaynardDepartment of Biological Sciences, Rensselaer Polytechnic Institute, Troy, New York, USA.
Nicole L Butler *Department of Chemistry and Chemical Biology, Rensselaer Polytechnic Institute, Troy, New York, USA.
Takeshi Ito *Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York, USA.
Adilson José da SilvaCenter for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York, USA.
Masatoshi MuraiDivision of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.
Tsute ChenThe Forsyth Institute, Cambridge, Massachusetts, USA.
Mattheos A G KoffasDepartment of Biological Sciences, Rensselaer Polytechnic Institute, Troy, New York, USA.
Hideto MiyoshiDivision of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.
Blanca BarqueraDepartment of Biological Sciences, Rensselaer Polytechnic Institute, Troy, New York, USA barqub@rpi.edu.
Rensselaer Polytechnic Institute · USKyoto University · JPHarvard University · USUniversidade Federal de São Carlos · BR

Funding

A new paradigm of respiration in the human gut BacteroidesR01AI132580 · NIAID · RENSSELAER POLYTECHNIC INSTITUTE · PI BARQUERA, BLANCA, COMSTOCK, LAURIE E · 2017 to 2020
$2.4M
NIAID NIH HHS R01 AI132580
6 · The paper itself

Abstract

Korormicin is an antibiotic produced by some pseudoalteromonads which selectively kills Gram-negative bacteria that express the Na

Indexed as

AntibiosisAliivibrio fischeriAnti-Bacterial AgentsBacterial ProteinsBacteroides fragilisBacteroides thetaiotaomicronFatty Acids, UnsaturatedFlavin-Adenine DinucleotideGene ExpressionLactonesMicrobial Sensitivity TestsModels, MolecularOperonOxidation-ReductionProtein Structure, SecondaryPseudoalteromonasAnti-Bacterial AgentsBacterial ProteinsFatty Acids, UnsaturatedFlavin-Adenine DinucleotidekorormicinLactonesNADH dehydrogenase (quinone)Quinone ReductasesReactive Oxygen SpeciesSodium-Potassium-Exchanging ATPaseantibiotickorormicinNa+-NQRreactive oxygen species

Identifiers

PMID30858300
PMCPMC6509656
OpenAlexW2921248067

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.