Evidence map›Paper›PMID 30858217›Full record

ArticleAntimicrobial agents and chemotherapy2019

Safety and Efficacy of Prolonged Use of Dalbavancin in Bone and Joint Infections.

L Morata, J Cobo, M Fernández-Sampedro, P Guisado Vasco, E Ruano, J Lora-Tamayo, M Sánchez Somolinos, P González Ruano, A Rico Nieto, A Arnaiz and 21 more

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
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  8. Article
  9. Review
  10. Study of the release kinetics of dalbavancin from bone allografts.Journal of materials science. Materials in medicine · 2025
    Article
  11. Article
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  13. Article
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  16. Off-label use of dalbavancin in children: a case series.The Journal of antimicrobial chemotherapy · 2024
    Article
  17. Review
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

L MorataDepartment of Infectious Diseases, Hospital Clínic of Barcelona, IDIBAPS, University of Barcelona, Barcelona, Spain lmorata@clinic.cat.
J CoboDepartment of Infectious Diseases, Hospital Ramón y Cajal, Madrid, Spain.
M Fernández-SampedroInfectious Diseases Unit, Department of Medicine, Hospital Universitario Marques de Valdecilla, Santander, Spain.
P Guisado VascoDepartment of Infectious Diseases, Complejo Hospitalario Quirón Ruber Juan Bravo, Madrid, Spain.
E RuanoDepartment of Infectious Diseases, Hospital Universitario de Getafe, Madrid, Spain.
J Lora-TamayoDepartment of Internal Medicine. Instituto de Investigación Sanitaria Hospital 12 de Octubre (i+12), Hospital Universitario 12 de Octubre, Madrid, Spain.
M Sánchez SomolinosDepartment of Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
P González RuanoDepartment of Infectious Diseases, Hospital Infanta Sofía, Madrid, Spain.
A Rico NietoDepartment of Infectious Diseases and Clinical Microbiology, Hospital Universitario La Paz, Madrid, Spain.ORCID 0000-0002-4364-2973
A ArnaizClínica Mompía, Santander, Spain.
M Estébanez MuñozUnit of Infectious Diseases, Internal Medicine, Hospital Central de la Defensa Gómez Ulla, Madrid, Spain.
M E Jiménez-MejíasClinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville, University of Seville/CSIC/University Hospital Virgen del Rocio, Seville, Spain.
A B Lozano SerranoTropical Diseases Unit, Hospital de Poniente, Almería, Spain.
E MúñezDepartment of Internal Medicine and Infectious Diseases, Hospital Universitario Puerta de Hierro, Madrid, Spain.
D Rodriguez-PardoDepartment of Infectious Diseases, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
R ArgelichDepartment of Internal Medicine, Centro Médico Téknon, Barcelona, Spain.
A ArroyoInfectious Diseases Unit, Complejo Hospitalario de Jaén, Jaén, Spain.
J M BarberoDepartment of Internal Medicine, Hospital Príncipe de Asturias, Universidad de Alcalá, Madrid, Spain.
F CuadraUnit of Infectious Diseases, Department of Internal Medicine, Complejo Hospitalario Universitario de Toledo, Toledo, Spain.
A Del ArcoDepartment of Internal Medicine, Hospital Costa del Sol, Marbella, Spain.
M D Del ToroClinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Hospital Universitario Virgen Macarena, Seville, Spain.
L GuioUnit of Infectious Diseases, Hospital Universitario Cruces, Bilbao, Spain.
D Jimenez-BeattyDepartment of Internal Medicine, Hospital Vithas Nuestra Señora de Fátima, Pontevedra, Spain.
N LoisDepartment of Internal Medicine, Hospital Universitario Severo Ochoa, Madrid, Spain.
O MartinDepartment of Internal Medicine, Hospital Universitario Fundación Alcorcón, Alcorcón, Spain.
R M Martínez AlvarezUnit of Infectious Diseases, Internal Medicine, Hospital Universitario Miguel Servet, Zaragoza, Spain.
F J Martinez-MarcosUnit of Infectious Diseases, Hospital Juan Ramón Jiménez, Huelva, Spain.
L PorrasDepartment of Internal Medicine, General Universitario Ciudad Real, Ciudad Real, Spain.
M RamírezDepartment of Internal Medicine, Hospital Universitario Arnau de Vilanova, Lleida, Spain.
J Vergas GarcíaDepartment of Internal Medicine and Infectious Diseases, Hospital San Carlos, Madrid, Spain.
A SorianoDepartment of Infectious Diseases, Hospital Clínic of Barcelona, IDIBAPS, University of Barcelona, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dalbavancin is a lipoglycopeptide with potent activity against Gram-positive microorganisms, a long half-life, a favorable safety profile, and a high concentration in bone, which makes it an interesting alternative for treatment of osteoarticular infections. We performed a multicentric retrospective study of all patients with an osteoarticular infection (septic arthritis, spondylodiscitis, osteomyelitis, or orthopedic implant-related infection) treated with at least one dose of dalbavancin between 2016 and 2017 in 30 institutions in Spain. In order to evaluate the response, patients with or without an orthopedic implant were separated. A total of 64 patients were included.

Indexed as

AgedBone and BonesFemaleGram-Positive BacteriaHumansJointsMaleMicrobial Sensitivity TestsMiddle AgedOsteomyelitisStaphylococcus aureusStaphylococcus epidermidisTeicoplanindalbavancinTeicoplaninbone and joint infectionsdalbavancinosteomyelitisprosthetic joint infection

Identifiers

PMID30858217
PMCPMC6496098

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.