Evidence map›Paper›PMID 30858162›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

More Is Less: Increased Processing of Unwanted Memories Facilitates Forgetting.

Tracy H Wang, Katerina Placek, Jarrod A Lewis-Peacock

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06460207 (A 4-day Study of Neurofeedback Training of Cognitive Control in Healthy Adults), which is not on this map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06460207 naunknown statusnot on this mapstarted 2024, after this paper: background citation

A 4-day Study of Neurofeedback Training of Cognitive Control in Healthy Adults

TypeinterventionalSponsorUniversity of Texas at AustinRan2024 to 2025Enrolled40ConditionsNeurofeedback, Cognitive Training, Memory, Short-Term, Functional Magnetic Resonance Imaging (fMRI)ArmsfMRI neurofeedback
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 52 citations in OpenAlex.

  1. Emotion regulation modulates subsequent control of unwanted memories.Social cognitive and affective neuroscience · 2026
    Article
  2. Article
  3. Review
  4. A compressed code for memory discrimination.bioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Timescales of learning in prefrontal cortex.Nature reviews. Neuroscience · 2024
    Review
  9. Article
  10. Article
  11. Differential Recruitment of Inhibitory Control Processes by Directed Forgetting and Thought Substitution.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  12. A smartphone intervention that enhances real-world memory and promotes differentiation of hippocampal activity in older adults.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  13. Article
  14. Review
  15. Article
  16. The visual arrays task: Visual storage capacity or attention control?Journal of experimental psychology. General · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Tracy H WangDepartment of Psychology, Institute for Neuroscience, University of Texas at Austin, Austin, Texas 78712-0805, and tracy.wang@utexas.edu.ORCID 0000-0001-5182-688X
Katerina PlacekDepartment of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania 19104.ORCID 0000-0002-0832-6684
Jarrod A Lewis-PeacockDepartment of Psychology, Institute for Neuroscience, University of Texas at Austin, Austin, Texas 78712-0805, and.ORCID 0000-0002-9918-465X
The University of Texas at Austin · USUniversity of Pennsylvania · US

Funding

Biasing the Forgetting of Visual MemoriesR01EY028746 · NEI · UNIVERSITY OF TEXAS AT AUSTIN · PI LEWIS-PEACOCK, JARROD A · 2018 to 2022
$1.8M
Investigating the contributions of neural competition to intentional forgetting and real-time neurofeedbackF32NS096962 · NINDS · UNIVERSITY OF TEXAS AT AUSTIN · PI WANG, TRACY HSIANG YI · 2017 to 2019
$187k
NEI NIH HHS R01 EY028746NINDS NIH HHS F32 NS096962
6 · The paper itself

Abstract

The intention to forget can produce long-lasting effects. This ability has been linked to suppression of both rehearsal and retrieval of unwanted memories, processes mediated by the prefrontal cortex and hippocampus. Here, we describe an alternative account in which the intention to forget is associated with increased engagement with the unwanted information. We used pattern classifiers to decode human functional magnetic resonance imaging data from a task in which male and female participants viewed a series of pictures and were instructed to remember or forget each one. Pictures followed by a forget instruction elicited higher levels of processing in the ventral temporal cortex compared with those followed by a remember instruction. This boost in processing led to more forgetting, particularly for items that showed moderate (vs weak or strong) activation. This result is consistent with the nonmonotonic plasticity hypothesis, which predicts weakening and forgetting of memories that are moderately activated.

Indexed as

AdolescentAdultBrainBrain MappingFemaleGyrus CinguliHumansMagnetic Resonance ImagingMaleMemoryParietal LobePrefrontal CortexYoung AdultfMRIforgettingintentional forgettingmemoryMVPAnonmonotonic plasticity hypothesis

Identifiers

PMID30858162
PMCPMC6495131
OpenAlexW2794322154

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.