ArticleVirology journal2019
Comparative proteomic analysis provides new insight into differential transmission of two begomoviruses by a whitefly.
Article in Virology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 26 citations in OpenAlex.
- Rewiring the proteome of the Euscelidius variegatus holobiont in response to Flavescence dorée phytoplasma.Scientific reports · 2025Article
- Comparative transcriptome analysis of whiteflies raised onFrontiers in veterinary science · 2024Article
- Transcriptomic and Proteomic Analyses ofBiology · 2023Article
- Cassava begomovirus species diversity changes during plant vegetative cycles.Frontiers in microbiology · 2023Article
- Combined Transcriptomic and Proteomic Analysis ofInsects · 2021Article
- A vector whitefly endocytic receptor facilitates the entry of begomoviruses into its midgut cells via binding to virion capsid proteins.PLoS pathogens · 2020Article
- Plant-virus-insect tritrophic interactions: insights into the functions of geminivirus virion-sense strand genes.Proceedings. Biological sciences · 2020Article
- Characterization of Local and Systemic Impact of Whitefly (International journal of molecular sciences · 2020Article
- Applications of Proteomic Tools to Study Insect Vector-Plant Virus Interactions.Life (Basel, Switzerland) · 2020Review
- Transcriptome Analysis of Gene Expression Profiles ofInsects · 2020Article
- Molecular insight into cotton leaf curl geminivirus disease resistance in cultivated cotton (Gossypium hirsutum).Plant biotechnology journal · 2020Article
- Article
- Gene Expression in the Salivary Gland ofFrontiers in cellular and infection microbiology · 2019Article
- Plant Antiviral Immunity Against Geminiviruses and Viral Counter-Defense for Survival.Frontiers in microbiology · 2019Review
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundViruses in the genus Begomovirus (Family Geminiviridae) include many important economic plant viruses transmitted by whiteflies of the Bemisia tabaci species complex. In general, different begomoviruses may be acquired and transmitted by the same whitefly species with different efficiencies. For example, the species Mediterranean (MED) in this whitefly species complex transmits tomato yellow leaf curl virus (TYLCV) at a higher efficiency than papaya leaf curl China virus (PaLCuCNV). However, the proteomic responses of whitefly to the infection of different begomoviruses remain largely unknown.
methodsWe used iTRAQ-based proteomics coupled with RT-qPCR to investigate and compare responses of the MED whitefly to the infection of TYLCV and PaLCuCNV.
resultsTotally, 259, 395 and 74 differently expressed proteins (DEPs) were identified in the comparisons of TYLCV-infected vs. un-infected, PaLCuCNV-infected vs. un-infected, and TYLCV-infected vs. PaLCuCNV-infected whiteflies, respectively. These proteins appear associated with catabolic process, metabolic process, transport, defense response, cell cycle, and receptor. The comparisons of TYLCV-infected vs. un-infected and PaLCuCNV-infected vs. un-infected shared some similar DEPs, indicating possible involvement of laminin subunit alpha, dystroglycan, integrin alpha-PS2 and cuticle proteins in viral transport as well as the role of putative defense proteins 3 and PITH in anti-viral response. However, 20S proteasome subunits associated with regulation of virus degradation and accumulation were up-regulated in PaLCuCNV-infected but not in TYLCV-infected whiteflies, which may be related to the constraints of PaLCuCNV accumulation in MED.
conclusionsThese findings provide valuable clues for unravelling the roles of some whitefly proteins in begomovirus transmission.
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