Evidence map›Paper›PMID 30857477›Full record

ReviewAnnual review of neuroscience2019

Probing Computation in the Primate Visual System at Single-Cone Resolution.

A Kling, G D Field, D H Brainard, E J Chichilnisky

Open access · bronzeAbstract readReview
In one paragraph

Review in Annual review of neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Frontiers in cell and developmental biology · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. An update on retinal prostheses.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2020
    Review
  10. Color, Pattern, and the Retinal Cone Mosaic.Current opinion in behavioral sciences · 2019
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

A KlingDepartments of Neurosurgery and Ophthalmology, Stanford University School of Medicine, Stanford, California 94305, USA; email: ej@stanford.edu.
G D FieldDepartment of Neurobiology, Duke University School of Medicine, Durham, North Carolina 27710, USA.
D H BrainardDepartment of Psychology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
E J ChichilniskyDepartments of Neurosurgery and Ophthalmology, Stanford University School of Medicine, Stanford, California 94305, USA; email: ej@stanford.edu.
Stanford University · USDuke University · USUniversity of Pennsylvania · US

Funding

Core Grant for Vision ResearchP30EY019005 · NEI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI ALBRIGHT, THOMAS D · 2009 to 2018
$7.7M
COLOR CONSTANCY--REAL IMAGES AND EARLY VISUAL MECHANISMSR01EY010016 · NEI · UNIVERSITY OF PENNSYLVANIA · PI BRAINARD, DAVID H. · 1998 to 2018
$5.4M
Patterned Electrical Stimulation of the Retina for High-Resolution ProsthesesR01EY021271 · NEI · STANFORD UNIVERSITY · PI EDUARDO CHICHILNISKY · 2011 to 2026
$4.6M
Receptive Field Mosaics of Midget, Parasol and Small Bi-Stratified Ganglion CellsR01EY017992 · NEI · STANFORD UNIVERSITY · PI CHICHILNISKY, EDUARDO · 2007 to 2014
$3.2M
Analyses of retinal circuits after rod rescue in a mouse model of human blindnessR01EY027193 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHEN, JEANNIE, FIELD, GREGORY DARIN · 2016 to 2020
$2.7M
Light adaptation and circadian modulation of parallel processing in retinaR01EY024567 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FIELD, GREGORY DARIN · 2014 to 2018
$2.0M
NEI NIH HHS P30 EY019005NEI NIH HHS R01 EY010016NEI NIH HHS R01 EY017992NEI NIH HHS R01 EY021271NEI NIH HHS R01 EY024567NEI NIH HHS R01 EY027193
6 · The paper itself

Abstract

Daylight vision begins when light activates cone photoreceptors in the retina, creating spatial patterns of neural activity. These cone signals are then combined and processed in downstream neural circuits, ultimately producing visual perception. Recent technical advances have made it possible to deliver visual stimuli to the retina that probe this processing by the visual system at its elementary resolution of individual cones. Physiological recordings from nonhuman primate retinas reveal the spatial organization of cone signals in retinal ganglion cells, including how signals from cones of different types are combined to support both spatial and color vision. Psychophysical experiments with human subjects characterize the visual sensations evoked by stimulating a single cone, including the perception of color. Future combined physiological and psychophysical experiments focusing on probing the elementary visual inputs are likely to clarify how neural processing generates our perception of the visual world.

Indexed as

AnimalsColor VisionForm PerceptionPatch-Clamp TechniquesPhotic StimulationPrimatesRetinal Cone Photoreceptor CellsRetinal Ganglion CellsSingle-Cell AnalysisVision, OcularVisual Perceptionadaptive opticscolor visionphotoreceptorreceptive fieldretinasingle cone

Identifiers

PMID30857477
PMCPMC6996509
OpenAlexW2921749410

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.