Evidence map›Paper›PMID 30857408›Full record

ReviewAnnual review of analytical chemistry (Palo Alto, Calif.)2019

Recent Developments in Nanosensors for Imaging Applications in Biological Systems.

Guoxin Rong, Erin E Tuttle, Ashlyn Neal Reilly, Heather A Clark

Abstract readReview
In one paragraph

Review in Annual review of analytical chemistry (Palo Alto, Calif.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Nanotheranostics: application of nanosensors in diabetes management.Journal of diabetes and metabolic disorders · 2023
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Imaging techniques in nanomedical research.European journal of histochemistry : EJH · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Guoxin RongDepartment of Bioengineering, Northeastern University, Boston, Massachusetts 02115, USA; email: h.clark@northeastern.edu.
Erin E TuttleDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, USA.
Ashlyn Neal ReillyDepartment of Bioengineering, Northeastern University, Boston, Massachusetts 02115, USA; email: h.clark@northeastern.edu.
Heather A ClarkDepartment of Bioengineering, Northeastern University, Boston, Massachusetts 02115, USA; email: h.clark@northeastern.edu.

Funding

Optical Nanosensors Detect Neurotransmitter Release in the Peripheral Nervous SystemOT2OD024909 · OD · NORTHEASTERN UNIVERSITY · PI MONAGHAN, JAMES R · 2017 to 2021
$2.1M
Polymer-Free Nanosensors To Visualize Biochemical Dynamics in Dendritic SpinesR01NS081641 · NINDS · NORTHEASTERN UNIVERSITY · PI CLARK, HEATHER A · 2013 to 2017
$1.6M
Circulating Red Blood Cell Based Nanosensors for Continuous, Real-Time Drug MonitoringR01EB024186 · NIBIB · NORTHEASTERN UNIVERSITY · PI CLARK, HEATHER A, NIEDRE, MARK JONATHAN · 2018 to 2021
$1.6M
AChMRNS: Nanosensors for Chemical Imaging of Acetylcholine Using MRIUF1NS107713 · NINDS · NORTHEASTERN UNIVERSITY · PI CLARK, HEATHER A, FLASK, CHRISTOPHER A · 2018 to 2018
$1.6M
NIBIB NIH HHS R01 EB024186NIH HHS OT2 OD024909NINDS NIH HHS R01 NS081641NINDS NIH HHS UF1 NS107713
6 · The paper itself

Abstract

Sensors are key tools for monitoring the dynamic changes of biomolecules and biofunctions that encode valuable information that helps us understand underlying biological processes of fundamental importance. Because of their distinctive size-dependent physicochemical properties, materials with nanometer scales have recently emerged as promising candidates for biological sensing applications by offering unique insights into real-time changes of key physiological parameters. This review focuses on recent advances in imaging-based nanosensor developments and applications categorized by their signal transduction mechanisms, namely, fluorescence, plasmonics, MRI, and photoacoustics. We further discuss the synergy created by multimodal nanosensors in which sensor components work based on two or more signal transduction mechanisms.

Indexed as

AnimalsBiosensing TechniquesHumansMagnetic Resonance ImagingNanotechnologyOptical ImagingPhotoacoustic Techniquesbiosensingfluorescencemagnetic resonance imagingMRImultimodalphotoacousticsplasmonics

Identifiers

PMID30857408
PMCPMC6958676

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.