Evidence map›Paper›PMID 30857316›Full record

ReviewFoods (Basel, Switzerland)2019

Prebiotics: Definition, Types, Sources, Mechanisms, and Clinical Applications.

Dorna Davani-Davari, Manica Negahdaripour, Iman Karimzadeh, Mostafa Seifan, Milad Mohkam, Seyed Jalil Masoumi, Aydin Berenjian, Younes Ghasemi

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Foods (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 666 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
666citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

666 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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606 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dorna Davani-DavariPharmaceutical Biotechnology Incubator, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz 71348, Iran. Davani-davari15@yahoo.com.
Manica NegahdaripourDepartment of Pharmaceutical Biotechnology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz 71348, Iran. Manica.Negahdaripour@gmail.com.
Iman KarimzadehDepartment of Clinical Pharmacy, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz 71348, Iran. Iman.Karimzadeh12@gmail.com.
Mostafa SeifanFaculty of Science and Engineering, University of Waikato, Hamilton 3216, New Zealand. mseifan@waikato.ac.nz.
Milad MohkamBiotechnology Research Center, Shiraz University of Medical Sciences, Shiraz 71348, Iran. Milad.Mohkam47@yahoo.com.
Seyed Jalil MasoumiNutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz 71348, Iran. J.masoumi74@gmail.com.
Aydin BerenjianFaculty of Science and Engineering, University of Waikato, Hamilton 3216, New Zealand. Aydin.berenjian@waikato.ac.nz.
Younes GhasemiDepartment of Pharmaceutical Biotechnology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz 71348, Iran. ghasemiy@sums.ac.ir.

Funding

Shiraz University of Medical Sciences Shiraz University of Medical Sciences
6 · The paper itself

Abstract

Prebiotics are a group of nutrients that are degraded by gut microbiota. Their relationship with human overall health has been an area of increasing interest in recent years. They can feed the intestinal microbiota, and their degradation products are short-chain fatty acids that are released into blood circulation, consequently, affecting not only the gastrointestinal tracts but also other distant organs. Fructo-oligosaccharides and galacto-oligosaccharides are the two important groups of prebiotics with beneficial effects on human health. Since low quantities of fructo-oligosaccharides and galacto-oligosaccharides naturally exist in foods, scientists are attempting to produce prebiotics on an industrial scale. Considering the health benefits of prebiotics and their safety, as well as their production and storage advantages compared to probiotics, they seem to be fascinating candidates for promoting human health condition as a replacement or in association with probiotics. This review discusses different aspects of prebiotics, including their crucial role in human well-being.

Indexed as

fructo-oligosaccharidesgalacto-oligosaccharidesgut microbiotaprebioticsshort-chain fatty acids

Identifiers

PMID30857316
PMCPMC6463098

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.