Evidence map›Paper›PMID 30857289›Full record

ReviewBiology2019

Pinniped- and Cetacean-Derived ETosis Contributes to Combating Emerging Apicomplexan Parasites (

Rodolfo Villagra-Blanco, Liliana M R Silva, Iván Conejeros, Anja Taubert, Carlos Hermosilla

Open access · goldAbstract readReview
In one paragraph

Review in Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Molecular detection of Toxoplasma gondii and Neospora caninum in seabirds collected along the coast of Santa Catarina, Brazil.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2024
    Article
  3. Frontiers in immunology · 2023
    Article
  4. Article
  5. Dynamics of cell cycle proteins involved inFrontiers in immunology · 2023
    Article
  6. Article
  7. Pathogens (Basel, Switzerland) · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Biology · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Parasitology · 2020
    Article
  17. Article
  18. Frontiers in immunology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rodolfo Villagra-BlancoInstitute of Parasitology, Justus Liebig University Giessen, 35392 Giessen, Germany. Rodolfo.A.Villagra-Blanco@vetmed.uni-giessen.de.
Liliana M R SilvaInstitute of Parasitology, Justus Liebig University Giessen, 35392 Giessen, Germany. Liliana.Silva@vetmed.uni-giessen.de.ORCID 0000-0002-2217-9983
Iván ConejerosInstitute of Parasitology, Justus Liebig University Giessen, 35392 Giessen, Germany. Ivan.Conejeros@vetmed.uni-giessen.de.ORCID 0000-0002-9995-4757
Anja TaubertInstitute of Parasitology, Justus Liebig University Giessen, 35392 Giessen, Germany. Anja.Taubert@vetmed.uni-giessen.de.
Carlos HermosillaInstitute of Parasitology, Justus Liebig University Giessen, 35392 Giessen, Germany. Carlos.R.Hermosilla@vetmed.uni-giessen.de.
Justus-Liebig-Universität Gießen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leukocytes play a major role in combating infections either by phagocytosis, release of antimicrobial granules, or extracellular trap (ET) formation. ET formation is preceded by a certain leukocyte cell death form, known as ETosis, an evolutionarily conserved mechanism of the innate immune system also observed in marine mammals. Besides several biomolecules and microbial stimuli, marine mammal ETosis is also trigged by various terrestrial protozoa and metazoa, considered nowadays as neozoan parasites, which are circulating in oceans worldwide and causing critical emerging marine diseases. Recent studies demonstrated that pinniped- and cetacean-derived polymorphonuclear neutrophils (PMNs) and monocytes are able to form different phenotypes of ET structures composed of nuclear DNA, histones, and cytoplasmic peptides/proteases against terrestrial apicomplexan parasites, e.g.,

Indexed as

emerging marine diseasesETosisextracellular trapsmarine mammalsneozoan parasites

Identifiers

PMID30857289
PMCPMC6466332
OpenAlexW2921560132

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.