Evidence map›Paper›PMID 30857133›Full record

ArticleMolecules (Basel, Switzerland)2019

Simulating DNA Chip Design Using All-Electronic Graphene-Based Substrates.

Ernane de Freitas Martins, Gustavo Troiano Feliciano, Ralph Hendrik Scheicher, Alexandre Reily Rocha

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 11 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Ernane de Freitas MartinsInstitute of Theoretical Physics, São Paulo State University (UNESP), Campus São Paulo, 01140-070 São Paulo, Brazil. ernanefmg@gmail.com.ORCID 0000-0002-3892-4693
Gustavo Troiano FelicianoInstitute of Chemistry, São Paulo State University (UNESP), Campus Araraquara, 14800-060 Araraquara, Brazil. gtroiano@iq.unesp.br.
Ralph Hendrik ScheicherDivision of Materials Theory, Department of Physics and Astronomy, Uppsala University, SE-751 20 Uppsala, Sweden. ralph.scheicher@physics.uu.se.
Alexandre Reily RochaInstitute of Theoretical Physics, São Paulo State University (UNESP), Campus São Paulo, 01140-070 São Paulo, Brazil. alexandre.reily@unesp.br.ORCID 0000-0001-8874-6947
Uppsala University · SECentro Universitário de Araraquara · BRUniversidade Estadual Paulista (Unesp) · BR

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001Fundação de Amparo à Pesquisa do Estado de São Paulo 2011/11973-4
6 · The paper itself

Abstract

In this paper, we present a theoretical investigation of an all-electronic biochip based on graphene to detect DNA including a full dynamical treatment for the environment. Our proposed device design is based on the changes in the electronic transport properties of graphene interacting with DNA strands under the effect of the solvent. To investigate these systems, we applied a hybrid methodology, combining quantum and classical mechanics (QM/MM) coupled to non-equilibrium Green's functions, allowing for the calculations of electronic transport. Our results show that the proposed device has high sensitivity towards the presence of DNA, and, combined with the presence of a specific DNA probe in the form of a single-strand, it presents good selectivity towards specific nucleotide sequences.

Indexed as

DNAElectronicsGraphiteNanoporesOligonucleotide Array Sequence AnalysisQuantum TheoryDNAGraphiteDNA chipgraphenenon-equilibrium Green’s functionsQM/MM

Identifiers

PMID30857133
PMCPMC6429485
OpenAlexW2922189428

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.