Evidence map›Paper›PMID 30857124›Full record

Observational studyInternational journal of environmental research and public health2019

Anti-Müllerian Hormone Gene Polymorphism is Associated with Clinical Pregnancy of Fresh IVF Cycles.

Cheng-Hsuan Wu, Shun-Fa Yang, Hui-Mei Tsao, Yu-Jun Chang, Tsung-Hsien Lee, Maw-Sheng Lee

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. [Correlation analysis of vitamin D level and anti-Müllerian hormone in infertile female and the role in predicting pregnancy outcome].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2023
    Article
  5. Article
  6. Article
  7. Association betweenInternational journal of environmental research and public health · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Cheng-Hsuan WuInstitute of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan. 97528@cch.org.tw.
Shun-Fa YangInstitute of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan. ysf@csmu.edu.tw.ORCID 0000-0002-0365-7927
Hui-Mei TsaoDivision of Infertility Clinic, Lee Womens' Hospital, Taichung 406, Taiwan. cshn076@csh.org.tw.
Yu-Jun ChangEpidemiology and Biostatistics Center, Changhua Christian Hospital, Changhua 50006, Taiwan. 83686@cch.org.tw.
Tsung-Hsien LeeInstitute of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan. thlee@csmu.edu.tw.ORCID 0000-0001-8858-0916
Maw-Sheng LeeInstitute of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan. mslee@csmu.edu.tw.
Chung Shan Medical University Hospital · TWChanghua Christian Hospital · TWKaohsiung Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to examine the effects of single-nucleotide polymorphisms (SNPs) in the anti-Müllerian hormone (AMH) and AMH type II receptor (AMHRII) genes on in vitro fertilization (IVF) outcomes. In this prospective cohort study, we genotyped the AMH 146 T > G, AMHRII -482 A > G and AMHRII IVS1 +149 T > A variants in 635 women undergoing their first cycle of controlled ovarian stimulation for IVF. DNA was extracted from the peripheral blood of all participants, and the SNPs were genotyped by real-time polymerase chain reaction. The distributions, frequencies of genes, and correlation with clinical pregnancy of IVF were analyzed. The AMH 146 T > G G/G genotype in women was associated with a lower clinical pregnancy rate (T/T: 55.0%, T/G: 51.8%, G/G: 40.0%;

Indexed as

Fertilization in VitroPolymorphism, Single NucleotidePregnancy RateAdultAnti-Mullerian HormoneEthnicityFemaleGenotypeHumansPolymerase Chain ReactionPregnancyProspective StudiesReceptors, PeptideReceptors, Transforming Growth Factor betaTaiwanAnti-Mullerian Hormoneanti-Mullerian hormone receptorReceptors, PeptideReceptors, Transforming Growth Factor betaAMH polymorphismAMHRII polymorphismAnti-Müllerian hormoneAnti-Müllerian hormone type II receptorIVF outcomes

Identifiers

PMID30857124
PMCPMC6427679
OpenAlexW2921766079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.