ArticleThe Journal of organic chemistry2019
Transfer of Sequence Information and Replication of Diimine Duplexes.
Article in The Journal of organic chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- Template-Directed Synthesis of Recognition-Encoded Melamine Oligomers Using a Base-Filling Strategy.Journal of the American Chemical Society · 2025Article
- Covalent Template-Directed Synthesis: A Powerful Tool for the Construction of Complex Molecules.Chemical reviews · 2025Review
- Length and Sequence-Selective Polymer Synthesis Templated by a Combination of Covalent and Noncovalent Base-Pairing Interactions.Journal of the American Chemical Society · 2024Article
- Synthetically encoded complementary oligomers.Nature reviews. Chemistry · 2023Review
- Peptide Macrocyclization Guided by Reversible Covalent Templating.Chemistry (Weinheim an der Bergstrasse, Germany) · 2023Article
- Folding and Duplex Formation in Sequence-Defined Aniline Benzaldehyde Oligoarylacetylenes.Journal of the American Chemical Society · 2022Article
- H-Bond Templated Oligomer Synthesis Using a Covalent Primer.Journal of the American Chemical Society · 2022Article
- Origin of Species before Origin of Life: The Role of Speciation in Chemical Evolution.Life (Basel, Switzerland) · 2021Review
- Controlled mutation in the replication of synthetic oligomers.Chemical science · 2021Article
- Solid-Phase Synthesis of Sequence-Defined Informational Oligomers.The Journal of organic chemistry · 2020Article
- Sequence information transfer using covalent template-directed synthesis.Chemical science · 2019Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The ability of the biopolymers RNA and DNA to store and transfer information is essential to life. Herein, we demonstrate template-directed replication in a set of dimer duplexes that use reversible covalent bonds to form base-pairing interactions. Binary sequence information was encoded as a sequence of aniline and benzaldehyde subunits linked together by a diethynyl benzene backbone. These dimers formed sequence-specific, imine-linked duplexes, which could be separated and used as templates for the synthesis of daughter duplexes with identical sequences.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.