ArticleNuclear medicine communications2019
Gated single-photon emission computed tomography myocardial perfusion imaging is superior to computed tomography attenuation correction in discriminating myocardial infarction from attenuation artifacts in men and right coronary artery disease.
Article in Nuclear medicine communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic Effect of Attenuation Correction in Myocardial Perfusion Imaging in Different Coronary Arteries: A Systematic Review and Meta-Analysis.Frontiers in cardiovascular medicine · 2021Pooled it
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Authors and funding
12 authors.
Funding
Abstract
backgroundIn single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) studies, attenuation artifacts frequently cause false positives, which can be partially overcome by computed tomography attenuation correction (CT-AC) or gated acquisition [gated myocardial perfusion imaging (GMPI)]. The purpose of this study is to evaluate their relative diagnostic performances for coronary artery disease (CAD). PATIENTS AND
methodsWe enrolled 181 patients who underwent gated SPECT with CT-AC in this study. Two observers who were blinded to the clinical data interpreted the GMPI and CT-AC images. Coronary angiography was considered as the reference standard. The diagnostic efficacy was evaluated based on sex, BMI, and individual coronary arteries.
resultsThe diagnostic accuracy of GMPI was higher than that of nonattenuation correction overall, as well as for men, overweight individuals, and right CAD (P<0.05). Compared with CT-AC, GMPI overall had a higher specificity (96.3 vs. 86.9%, P=0.014) but the same sensitivity, achieving an increased accuracy and area under the curve (AUC, P>0.05). For diagnosing right CAD, GMPI had a higher diagnostic efficacy (AUC: 0.733 vs. 0.596, P<0.001) because of its higher sensitivity (52.0 vs. 26.0%, P=0.008); for men, the diagnostic efficacy of GMPI was significantly higher than that of CT-AC (AUC: 0.754 vs. 0.681, P=0.038).
conclusionBoth CT-AC and GMPI led to an increased diagnostic efficacy compared with nonattenuation correction in differentiating attenuation artifacts from fixed perfusion defects. These improvements were, however, more obvious for GMPI than for CT-AC, especially in men and right CAD.
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