SynthesisMedicine2019
The use of Indocyanine green in endocrine surgery of the neck: A systematic review.
Synthesis in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Intraoperative fluorescence in solid head and neck cancer: A scoping review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- Incident Dark-Field (IDF) Illumination Microscopy as a Novel Tool for Real-Time, Dye-Free Parathyroid Perfusion Assessment in Thyroid Surgery.Annals of surgical oncology · 2025Article
- Indocyanine green fluorescence-guided sentinel lymph node biopsy: A systematic review.World journal of otorhinolaryngology - head and neck surgery · 2025Review
- Fluorescence Imaging Using Deep-Red Indocyanine Blue, a Complementary Partner for Near-Infrared Indocyanine Green.Chemical & biomedical imaging · 2024Article
- Silicon-Rhodamine Functionalized Evocalcet Probes Potently and Selectively Label Calcium Sensing ReceptorsACS pharmacology & translational science · 2024Article
- Techniques for Thyroidectomy and Functional Neck Dissection.Journal of clinical medicine · 2024Review
- Fluorescence-guided minimally-invasive resection of abdominal paragangliomas using indocyanine green.Scientific reports · 2024Article
- Intraoperative indocyanine green angiography for predicting postoperative hypoparathyroidism.Surgical endoscopy · 2023Article
- Surgery for Sporadic Primary Hyperparathyroidism: Evolution over the Last Twenty Years in a Monocentric Setting.Cancers · 2023Article
- Indocyanine green fluorescence guided resection of parathyroid adenoma of the carotid sheath: a case report and review of the literature.Gland surgery · 2023Article
- Assessing Parathyroid Gland Viability and Predicting Postoperative Hypoparathyroidism in Thyroid Surgery: The Utility of Indocyanine Green Angiography.Sisli Etfal Hastanesi tip bulteni · 2023Article
- TOETVA parathyroid autofluorescence detection: hANDY-i endoscopy attachment.Frontiers in endocrinology · 2023Article
- Spontaneous Transfer of Indocyanine Green from Liposomes to Albumin Is Inhibited by the Antioxidant α-Tocopherol.Langmuir : the ACS journal of surfaces and colloids · 2022Article
- Autofluorescence of parathyroid glands during endocrine surgery with minimally invasive technique.Journal of endocrinological investigation · 2022Article
- A pilot feasibility study to assess vascularity and perfusion of parathyroid glands using a portable hand-held imager.Lasers in surgery and medicine · 2022Article
- The utility of indocyanine green (ICG) for the identification and assessment of viability of the parathyroid glands during thyroidectomy.Updates in surgery · 2022Observational
- Total thyroidectomy with intraoperative neural monitoring and near-infrared fluorescence imaging.Langenbeck's archives of surgery · 2021Article
- Deuterated Indocyanine Green (ICG) with Extended Aqueous Storage Shelf-Life: Chemical and Clinical Implications.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Article
- Fluorescence Image-Guided Surgery for Thyroid Cancer: Utility for Preventing Hypoparathyroidism.Cancers · 2021Review
- Multi-Wavelength Fluorescence in Image-Guided Surgery, Clinical Feasibility and Future Perspectives.Molecular imagingReview
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe insufficient reliability of preoperative imaging technology and limited convenience of intraoperative visualizing techniques have been associated with difficulty in surgical navigation in neck endocrine surgery. Indocyanine green (ICG) fluorescence imaging has stood out as the real-time intraoperative guide amidst research for novel modalities, with an emerging use in endocrine surgery.
methodsWe performed a systematic review of the PubMed, Scopus and Embase databases, to identify published studies on parathyroid and thyroid operations employing ICG. Well-described articles were selected according to 7 criteria and analyzed per operation type and organ structure.
resultsTwenty-one articles matched our selection criteria. Dosage, equipment, and techniques are well-described in literature. ICG was found to significantly enhance the surgical experience and outcomes. Occasional discrepancy among studies was attributed to the lack of standard quantification of values and divergence of study designs.
conclusionThe most successful applications of ICG are:Future research is needed for standard quantification of fluorescence intensity and objective comparisons.
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