Evidence map›Paper›PMID 30855227›Full record

ArticleeLife2019

Spatiotemporal establishment of dense bacterial colonies growing on hard agar.

Mya R Warren, Hui Sun, Yue Yan, Jonas Cremer, Bo Li, Terence Hwa

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 123 citations in OpenAlex.

  1. Article
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  4. Review
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  8. Dissecting the physics of bacterial biofilms with agent-based simulations.Current opinion in solid state & materials science · 2025
    Article
  9. Article
  10. Colony pattern multistability emerges from a bistable switch.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Article
  12. Review
  13. Spatial population dynamics of bacterial colonies with social antibiotic resistance.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Comprehensive Characterization ofInternational journal of molecular sciences · 2024
    Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Mya R Warren *Department of Physics, University of California, San Diego, La Jolla, United States.
Hui Sun *Department of Physics, University of California, San Diego, La Jolla, United States.ORCID 0000-0003-3137-3873
Yue YanDepartment of Mathematics, University of California, San Diego, La Jolla, United States.
Jonas CremerDepartment of Physics, University of California, San Diego, La Jolla, United States.
Bo LiDepartment of Mathematics, University of California, San Diego, La Jolla, United States.
Terence HwaDepartment of Physics, University of California, San Diego, La Jolla, United States.ORCID 0000-0003-1837-6842
University of California San Diego · USFudan University · CN

Funding

Quantitative Studies of Bacterial Growth PhysiologyR01GM095903 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HWA, TERENCE · 2011 to 2023
$3.8M
National Science Foundation DMS-1319731National Science Foundation DMS-1620487NIGMS NIH HHS R01 GM095903Simons Foundation 522790Simons Foundation 542387
6 · The paper itself

Abstract

The physical interactions of growing bacterial cells with each other and with their surroundings significantly affect the structure and dynamics of biofilms. Here a 3D agent-based model is formulated to describe the establishment of simple bacterial colonies expanding by the physical force of their growth. With a single set of parameters, the model captures key dynamical features of colony growth by non-motile, non EPS-producing

Indexed as

AgarCulture MediaMechanical PhenomenaComputer SimulationEscherichia coliSpatio-Temporal AnalysisAgarCulture Mediabacterial colonycell growthcomputational biologycomputational modelingE. colisystems biology

Identifiers

PMID30855227
PMCPMC6411370
OpenAlexW2921290863

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.